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| The Comparison Between C-reactive Protein、Fibrinogen in Cerebral Infarction Patients with Bone Fracture and in Cerebral Infarction Patients without Bone Fracture |
| The Forth Hospital of Baotou，Baotou 014030，China |
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Abstract Objective：To compare the level of C-reactive protein and Fibrinogen in the cerebral infarction patients with bone fracture and cerebral infarction patients without bone fracture.Method：The patients in advanced neurology and orthopedic department were selected， including the old bone fracture patients developed cerebral infarction patients，and divided into patients with bone fracture group and patients without bone fracture group，70 cases in each group.The second day after admission the blood was collected， the level of C-reactive protein and Fibrinogen were measured，then statistic analysis of them was used.Result：The level of C-reactive protein and Fibrinogen in patients with bone fracture were higher than patients without bone fracture，they were significiant correlation with cerebral infarction volume，in the same cerebral infarction volume，the level of C-reactive protein and Fibrinogen in patients with
bone fracture were higher than patients without bone fracture.Level of CRP and FIB had positively correlated with nerve function damage degree（light，medium，heavy），and the same nerve function damage degree of combined fracture significantly higher than the unincorporated fracture group，the two groups were compared， the difference was statistically significant（P<0.05）.So，higher level of C-reactive protein and Fibrinogen in the old patients after bone fracture were danger factors， they could lead to cerebral infarction.Conclusion：C-reactive protein and Fibrinogen were involved in the pathologic process of cerebral infarction，level of C-reactive protein and Fibrinogen may be helpful as objective guides to judging the size of infarction area， nerve function damage degree and prognosis.At the same time， orthopedic surgeon can measure them to prevent the happen of cerebral infarction.
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