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Abstract Objective： To explore the efficacy of the combination of glargine insulin and metformin extended release tablets in the treatment of newly diagnosed type 2 diabetes. Method： 65 patients with newly diagnosed type 2 diabetes were admitted in our community from January 2013 to December and were randomly divided into two groups， the control group was given a daily extended release metformin tablets and nightly subcutaneous Novolin N， the study group was given a daily extended release metformin tablets and nightly subcutaneous insulin glargine. Fasting blood glucose （FBG）， two hours after meal blood glucose（ PBG） and glycosylated hemoglobin（ HbA1c） content of two groups before and after treatment were analyzed and compared. Result： The total efficiency rate of treatment of the study group was 90.9%，significantly higher than the control group of 71.9%， the difference was statistically significant （ P<0.01）；the indicators of the study group after treatment were significantly improved， and significantly than the control group the difference was statistically significant （P<0.05）. Conclusion： The combination of glargine insulin and metformin extended release tablets in the treatment of newly diagnosed type 2 diabetic has efficacy significantly and helpful to improve the symptoms，not only has good hypoglycemic effect， and has a lower incidence of hypoglycemia， security is good，it is worthy promotion and application.
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