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| Effect of Dynamic Serum Procalcitonin Monitoring on the Optimization of Antibacterial Treatment in Intracerebral Hemorrhage Fever Patients |
| Central People’s Hospital of Zhanjiang，Zhanjiang 524037，China |
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Abstract Objective： To discuss the effect of dynamic serum procalcitonin（PCT） monitoring on the optimization of antibacterials treatment in intracerebral hemorrhage fever patients and provide references for rational drug use in the clinical.Method：68 patients with intracerebral hemorrhage complicating pyrexia in our hospital from January 2014 to January 2015 were selected and randomly divided into two groups，34 cases in the PCT group were treated with antibacterial according to the dynamic serum procalcitonin（PCT），34 patients in the control group were given experiential antibacterial treatment according to patients’ clinical situations and laboratorial examination.The survey conducted 28 days，PCT values of the PCT group and the usage of antibacterial in the two groups were recorded and contrasted.Result：Serum procalcitonin of the PCT group decreased gradually with the use of antibacterials.There were significant differences between the PCT group and the control group in the aspects of antibacterial usage ratio，antibacterial using density（AUD），the costs of antibacterial and the percentage of the costs（P<0.05）.Conclusion：Making antibiotic treatment strategy according to the dynamic procalcitonin valves can optimize the usage of antibacterials in the treatment of intracerebral hemorrhage，reduce the AUD，usage ratio and the costs of antibacterials.It presents instructive meaning for avoiding excessively using of antibacterials and reducing drug-fast of bacteria during treatment.
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