Abstract Objective： To discuss the clinical curative effect of using different treatment method of azithromycin treatment of children with Mycoplasma infection. Method： 166 patients with mycoplasma infection in our hospital from 2013 January to December were randomly selected as the objects， and randomly divided into observation group and control group， the control group contained 83 cases， which was given treatment of azithromycin based conventional treatment methods： the first dose of 20 mg/kg Azithromycin injection， intravenous infusion of the drug， sustained 5D， 1 time/d， after 4D dosage for the first half， after 4D of withdrawal， again in the treatment of 3D by using this method； the observation group contained 83 cases， which carries on the treatment method using the same control group based on the conventional treatment， difference was that， stop drug 4D in children， again in the treatment of 5D using this method.
At the end of treatment， the clinical efficacy， duration of hospitalization， and various symptoms disappear time of the two groups was compared. Result： The cure rate and total effective rate of the observation group p was 84.3%（ 70 cases），95.1%（ 79 cases）， and that of the control group was 79.5%（ 66 cases）， 91.5%（ 76 cases）， there was no statistically significant difference. The hospitalization time and a variety of diseases disappear time of the observation group was lower than that of the control group， there was statistically significant difference（ P<0.05）. Conclusion： The use of azithromycin intravenous infusion therapy for children with 5D after stopping drug， 4D， again in the treatment of 5D by using this method， can effectively shorten the symptom disappearance time， get favorable comments from the families of the children， worthy of promotion and application in clinical.
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