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Long-term Effect of Atovastatin Calcium on Carotid Atherosclerosis Plaque in Patients with Acute Cerebral Infarction |
Lu’an Municipal Hospital, Lu’an 237000,China |
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Abstract Objective:To evaluate the long-term effect of atovastatin calcium on carotid atherosclerosis plaque in patients with acute cerebral infarction.Method:100 cases of patients in our hospital were chosen as the experimental objects.,and were divided into experimental group and control group,control group were treated with routine treatment,and the experimental group were treated with atovastatin calcium on the basis of control group,the TC,TG,LDL,HDL,hs-CRP,IMT,plaque area and adverse reaction between two group were compared.Result:After 12 months’treatment,TC,TG,LDL,HDL,hs-CRP of the experimental group were statistically better than that of the control group(P<0.05).The plaque area and IMT of the experimental group were statistically lower than that of the control group(P<0.05).The adverse reaction between two group had no significant difference( 字2=1.375,P<0.05).Conclusion:Atovastatin calcium could improve the blood lipid level,reduce the inflammation response,has a stable and promote the ablation effect on plaque.
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