Abstract Objective：To study the influence of clinical pharmacist intervention model on compliance，clinical efficacy and life quality of warfarin.Method：60 patients with chronic AF were selected in our hospital from June 2013 to June 2014 as the research object，and were divided into observation group and control group according to the discharge order，30 cases in each group.The observation group was treated with clinical pharmacist intervention，control group was treated without pharmacists，drug compliance，efficacy and life quality of two groups were compared. Result：The total compliance of the observation group was 86.67%，significantly higher than the control group of 63.33%，the difference was statistically significant（P<0.05）；occurrence rates of thrombosis and bleeding rates of observation group were 0 and 6.67%，significantly lower than control group of 13.33% and 26.67%，the differences were statistical significance（P<0.05）； when the observation group discharged after 1 years，the scores were significantly higher than those in the control group，the differences were statistically significant（P<0.05）.Conclusion：Pharmacists intervention mode to accept warfarin treatment can improve the medication compliance and curative effect，improve the quality of life of patients，has high clinical value.
