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Abstract Objective：To evaluate the impact of medicines policy on rational use of drugs by comparing the essential drugs and antibiotics.Method：A total of prescriptions in outpatients and emergency departments of hospital records，2011 was selected as a policy implementation group，2012 as part of the implementation of phase 1 group，2013 as part of the implementation of phase 2 group，before and after the implementation of the control study，the effectiveness and feasibility of the implementation of the policy were investigated.Result：The usage of prescriptions and essential drugs was 51% and 33% respectively.The implementation of phase 2 the intensity of use of antimicrobial agents for 38.67%，compared with the former of 73.06% were decreased significantly，the difference between the two groups had statistically significance（P<0.05）.Type I incision surgery to prevent use of antibacterial drugs proportion had decreased significantly，the difference had statistically significance（P<0.01）. Conclusion：Medicines policy and intervention measures have some effect on the promotion of rational drug use.
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