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Abstract Objective：To study the clinical significance of DSA-guided percutaneous nucleus pulposus clamp combined with ozone ablation in the treatment of cervical disc hermiation.Method：86 patients with cervical intervertebral disc hermiation of C4/5，C5/6，C6/7 or C7/T1 were selected as the research objects.43 patients with cervical intervertebral disc hermiation of C6/7 or C7/T1 in the clamp group（group A） were treated with DSA-guided percutaneous nucleus pulposus clamp combined with ozone ablation.43 patients with cervical intervertebral disc hermiation of C4/5 or C5/6 in the radio frequency group（group B） were treated with radiofrequency thermocoagulation combined with ozone ablation.The VAS scores and clinical effects in different stages of the two groups were observed and compared.Complications during and after the operation were recorded.Result：24 hours，72 hours，1 week，4 weeks and 12 weeks after the operation，the VAS scores of the two groups were lower than before treatment.4 weeks and 12 weeks after the operation， the VAS scores of group A were lower than those of group B.The differences above were all statistically significant（P<0.05）.12 weeks after the operation，the excellent and good rate of group A was 91.3%，group B was 80.5%.The failure rate of group A was 8.7%，group B was 19.5%.There were no serious complications happened in the two groups.Conclusion：At present，DSA-guided percutaneous nucleus pulposus clamp combined with ozone ablation is the most safe and effective treatment method for cervical intervertebral disc herniation.
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