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| To Investigate the Clinical Application of Combination Hemodialysis and Peritoneal Dialysis for End-stage Renal Disease |
| Fuyong People’s Hospital of Shenzhen，Shenzhen 518103，China |
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Abstract Objective：To investigate the therapeutic effect of combination of peritoneal dialysis and hemodialysis for end-stage renal disease.Method： 90 patients of end-stage renal disease were selected in our hospital as the research object from May 2012 to May 2014 and divided into three groups，combination group，peritoneal dialysis group and hemodialysis group， 30 cases in each group. One year follow-up，the three groups of patients’ complications ，biochemical indexes during hospitalization，and statistics of all patients with in one year survival rate and cause of death were observed， according to the quality of life of 1.2 KDQOL-SFTM scores of quality life on the survival of patients with analysis.Result：There were not statistically significant differences between combination group and peritoneal dialysis group and hemodialysis group in serum potassium and blood glucose level（P>0.05）. The combination group of urea nitrogen and creatinine levels compared with hemodialysis group had no significant difference（P>0.05），and compared with peritoneal dialysis group significantly decreased， the difference was statistically significant（P<0.05）.Combination group of hemoglobin and albumin levels were significantly higher than that of peritoneal dialysis group and hemodialysis group， the differences were statistically significant（P< 0.05）， between peritoneal dialysis group and hemodialysis group had no significant difference（ P>0.05）.The rate of complication in the combination group was significantly less than peritoneal dialysis group and hemodialysis group，the difference was statistically significant（P< 0.05），peritoneal dialysis group complication rate was higher than the hemodialysis group， there was significant difference between two groups （P<0.05）.Combination group of the survival rate of the patients was significantly higher than that of peritoneal dialysis group and hemodialysis group， the difference was statistically significant（P<0.05）， peritoneal dialysis group of the survival rate was lower than the hemodialysis group， but the difference had no statistical significance（P>0.05）.The combination group patients symptoms and discomfort of 12 items， affect daily life of 8 items， the working condition of 2 items， 3 items of social quality， function of 2 items，social function of 2 items， the energy status of 4 items were better than peritoneal dialysis group and hemodialysis group， the differences were statistically significant（P<0.05）， in which the blood dialysis group scored higher than peritoneal dialysis group， there was not significant difference between two groups （P<0.05）. The combination group 2 scores of pain was significantly less than peritoneal dialysis group and hemodialysis group， the difference was statistically significant（P<0.05）， but between peritoneal dialysis group and hemodialysis group was no statistical significance difference（P>0.05）.Conclusion： The combination group patients can stable internal environment condition， good effect， less complications，and it is worthy of clinical application.
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