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| Effect of Diaphragm Stimulation on Diaphragm Function in Patients with Ventilator Dependency Severe Craniocerebral Injury |
| CHEN Kaihua, LIU Qiaoping, YU Rongguo |
| First-author's address: Fujian Medical University Provincial Clinical Medical College, Fuzhou 350001, China |
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Abstract Objective: To study the effect of diaphragm stimulation on diaphragm function in patients with ventilator dependency severe craniocerebral injury. Method: A total of 80 patients with ventilator dependency severe craniocerebral injury who were admitted to Fujian Provincial Hospital from January 2020 to December 2022 were divided into two groups according to random number table method. The control group (n=40) received routine symptomatic treatment, and the research group (n=40) received diaphragm stimulation on the basis of the control group. The diaphragm function, respiratory condition, oxidative stress response and prognostic situation were compared between the two groups. Result: After treatment, the diaphragm thickness and thickness ratio, diaphragm displacement after calm breathing and deep inhalation in the research group were higher than those in the control group (P<0.05). After treatment, the maximal inspiratory pressure and expiratory pressure and superoxide dismutase (SOD) levels in the research group were higher than those in the control group, while the rapid shallow breathing index (RSBI), the levels of malondialdehyde (MDA) and glutathione (GSH) were lower than those in the control group (P<0.05). The re-entry ventilator rate of the research group was lower than that of the control group, and the treatment time in the intensive care unit (ICU) was shorter than that of the control group (P<0.05). Conclusion: Diaphragm stimulation can effectively improve the diaphragm function and respiratory condition of patients with ventilator dependency severe craniocerebral injury, reduce oxidative stress response and improve their prognosis.
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Received: 12 April 2023
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