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| Effect of Huoxue Tongluo Heji Combined with Conventional Western Medicine on Cerebral Infarction and Its Influence on Hemodynamics |
| ZHANG Hongli, WANG Aiqin |
| First-author's address: Xuzhou Hospital of TCM, Jiangsu Province, Xuzhou 221000, China |
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Abstract Objective: To explore the effect of Huoxue Tongluo Heji combined with conventional western medicine on cerebral infarction and its influence on hemodynamics. Method: A total of 86 patients with cerebral infarction admitted to Xuzhou Hospital of TCM from January 2021 to January 2022 were selected and divided into observation group and control group using random number table method, with 43 cases in each group. The control group was treated with conventional western medicine, and the observation group was treated with Huoxue Tongluo Heji on the basis of the control group. The total effective rate, nerve function related score, hemodynamic index and serum related index of the two groups were compared. Result: The total effective rate of treatment in the observation group (97.67%) was higher than that in the control group (83.72%), the difference was statistically significant (P<0.05). Before treatment, there were no statistically significant differences in the NIHSS, MoCA and FMA scores between the two groups (P>0.05); 6 months after treatment, the NIHSS scores of both groups decreased, and the observation group was lower than that of the control group, MoCA scores and FMA scores were both increased, and the observation group were higher than those of the control group, the differences were statistically significant (P<0.05). Before treatment, there were no significant differences in whole blood high shear viscosity, whole blood low shear viscosity, plasma viscosity, hematocrit, fibrinogen and sedimentation rate between the two groups (P>0.05); 6 months after treatment, the indexes of both groups were decreased, and the observation group were lower than those of the control group, the differences were statistically significant (P<0.05). Before treatment, there were no significant differences in the levels of C reactive protein (CRP), interleukin-6 (IL-6), interleukin-8 (IL-8), vascular endothelial growth factor (VEGF), matrix metalloproteinase-9 (MMP-9) and neuron-specific enolase (NSE) between the two groups (P>0.05); 6 months after treatment, the levels of CRP, IL-6, IL-8, MMP-9
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Received: 11 January 2023
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