|
|
|
| Application of Dexmedetomidine Combined with Hydromorphone in Hysteroscopic Surgery under Laryngeal Mask without Muscle Relaxant General Anesthesia |
| PANG Lixia, WEN Laiyou, WU Zhen, CHEN Jianqing |
| Jiangyin People's Hospital, Jiangsu Province, Jiangyin 214400, China |
|
|
|
|
Abstract Objective: To investigate the effect of Dexmedetomidine combined with Hydromorphone application in hysteroscopic surgery under laryngeal mask without muscle relaxant general anesthesia. Method: From January to December 2021, 58 patients undergoing hysteroscopic surgery in Jiangyin People's Hospital under aryngeal mask without muscle relaxant general anesthesia were selected and randomly divided into Dexmedetomidine + Hydromorphone group (DH group) and Sufentanil group (SF group), 29 patients in each group. In the DH group, general anesthesia was induced with Dexmedetomidine 0.2 μg/kg intravenously (≥10 min) combined with Hydromorphone 0.02 mg/kg and Propofol 2.5 mg/kg intravenously. In the SF group, general anesthesia was induced with Sufentanil 0.3 μg/kg and Propofol 2.5 mg/kg intravenously, Propofol 6 mg/kg intravenous pump was used for anesthesia maintenance in both groups. Heart rate (HR) and mean arterial pressure (MAP) were recorded before induction of general anesthesia (T0), before the start of surgery (T1), 10 min after the start of surgery (T2) and at the end of surgery (T3) in both groups. Bispectral index (BIS) at T1, T2 and T3 were recorded in both groups, and the time of surgery, the time of recovery from the end of surgery and the occurrence of intraoperative body movements were recorded in both groups. Result: Compared with SF group, HR and MAP of DH group were higher than those of SF group at T1 and T2, BIS at T1 and T2 were lower than those of SF group, BIS at T3 was higher than that of SF group, the incidence of intraoperative body movement was lower than that of SF group, and the recovery time was shorter than that of SF group, the differences were statistically significant (P<0.05). Conclusion: The application of Dexmedetomidine 0.2 μg/kg intravenously (≥10 min) combined with Hydromorphone 0.02 mg/kg intravenously in hysteroscopic surgery under laryngeal mask without muscle relaxant general anesthesia is reasonable and effective, resulting in smooth intraoperative anesthesia and rapid awakening.
|
|
Received: 30 January 2023
|
|
|
|
|
|
|
