|
Abstract Objective：To observe the efficacy of combined Tongxiening granule and Golden Bifid for the treatment of patients with dominant-diarrhea irritable bowel syndrome.Method： Randomized and parallel-group study method was used， 75 IBS-D patients who met the inclusion criteria were divided into three groups： group A（ combined Tongxiening granule and Golden bifid tablets study group）， group B（ Tongxiening granule alone control group） and group C（ Golden bifid tablets alone control group）， 25 cases in each group. The symptoms of abdominal pain， diarrhea and global symptom were scored. The efficacy was determined by the changes of symptom scores. Result：After treatment for 4 weeks，compared the abdominal pain scores， diarrhea symptoms scores and total symptoms scores of three groups before and after treatment， the differences were statistically significant（P<0.01）. After treatment，compared the symptoms scores of three groups patients， group A had statistically significant differences with the other two groups（P<0.01）， but had no statistical differences between the group B and C（P>0.05）.Compared the effect of three groups， group A had statistically significant difference with the other two groups（P<0.05）， but had no statistical differences between the group B and C（P>0.05）.Conclusion：Adjunctive therapy of Tongxiening granule and Golden Bifid tablets for IBS-D obviously improve the core symptoms of patients， has a better curative effect and no adverse reaction.
|
|
|
|
|
|
