Abstract Objective：To explore the clinical effects of gastric and duodenal perforation by laparoscopic herniorrhaphy.Method：128 patients with gastric and duodenal perforation in our hospital were selected from April 2012 to March 2015，they were divided into the experiment group and the control group，64 cases in each group. The control group was treated by traditional laparotomy， the experiment group was treated by laparoscopic herniorrhaphy.The operation time， intraoperatve blood soss， postoperative anal exhaust time for the first time， post operation hospitalization duration，postoperative complication， postoperative recurrence and abnormal body temperature of two groups were compared. Result：The operation time of the experiment group was longer than the control group， the difference was statistically significant（P<0.05）.The intraoperatve blood soss， postoperative anal exhaust time for the first time and post operation hospitalization duration of the experiment group were lower than the control group， the differences were statistically significant（P<0.05）.The postoperative complication of experiment group was 9.38%，which was lower than 28.13% of the control group， the difference was statistically significant（P<0.05）.The postoperative recurrence and abnormal body temperature of experiment group were lower than the control group，the differences were statistically significant（P<0.05）. Conclusion：It has good clinical effects for the patients with gastric and duodenal perforation by laparoscopic herniorrhaphy， it can reduce the intraoperatve blood soss， postoperative anal exhaust time for the first time， post operation hospitalization duration and postoperative complication， but it takes longer operation time.
