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| Clinical Research of Erxieting in the Prevention of Antibiotic-associated Diarrhea |
| The Children’s Hospital of Changzhou City Affiliated to Nantong University，Changzhou 213003，China |
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Abstract Objective：To investigate the effect of Erxieting in the prevention of antibiotic-associated diarrhea. Method：230 children with pneumonia in our hospital from June 2013 to December 2013 were selected and randomly divided into two groups.118 cases in the prevention group were given Erxieting on the basis of antibiotics and symptomatic treatment.112 cases in the control group were given antibiotics and symptomatic treatment，Erxieting was given to them after the diarrhea occurred.The incidence of diarrhea and its severity，curative effect，duration of diarrhea，treatment course of diarrhea and the incidence rates in different time were compared between the two groups.Result：The incidence of diarrhea and its severity in the prevention group was lower than those in the control group，the curative effect of the prevention group was better than that of the control group，the duration and treatment course of diarrhea in the prevention group were shorter than those in the control group，the incidence rates in different time of the prevention group were lower than those of the control group，the differences above were all statistically significant（P<0.05）.There were no adverse reactions in the two groups.Conclusion：Erxieting can be used to prevent antibiotic-associated diarrhea in infants，its early application can reduce the duration and treatment course of diarrhea.It is good for patients’ speedy recovery.
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