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| Positive Rate and Clinical Significance of Incomplete Antibody after Repeated Transfusion |
| The Affiliated Hospital of Jinggangshan University，Ji’an 343600，China |
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Abstract Objective：To analyze the positive rate and clinical significance of incomplete antibody after repeated transfusion. Method：1600 people with repeated blood transfusion in our hospital from June 2013 to March 2015 were selected as the observation group.1600 people who received blood transfusion for the first time were selected as the control group at the same time.The incomplete antibody in the blood samples of the two groups were screened.The positive rate of incomplete antibody and its relationship with adverse reactions of blood transfusion were observed.The antibody types of the observation group were analyzed，the positive situation of anti-D，autoantibodies，anti-Ec，anti-C，anti-c，anti-e，anti-M，anti-JKa and unknown antibody in patients with different blood transfusion times were observed. Result：The positive rate of incomplete antibody in the observation group was significantly higher than that in the control group，the difference was as statistically significant（ P<0.05）.The positive rates of incomplete antibody in patients with 3 to 5 times and 6 to 10 times of blood transfusion were lower than that in patients with more than 15 times of blood transfusion，the differences were statistically significant（P<0.05）.The adverse reaction of blood transfusion in patients with positive incomplete antibody was higher than that in patients with negative incomplete antibody，the difference was statistically significant（ P<0.05）.In the observation group，patients with 3 to 5 times of blood transfusion had 3 kinds of antibodies，patients with 6 to 10 times of blood transfusion had 4 kinds of antibodies，patients with 11 to 15 times of blood transfusion had 6 kinds of antibodies，patients with more than 15 times of blood transfusion had 7 kinds of antibodies. Conclusion：According with the increasing of the times of transfusion，the occurrence rates of positive incomplete antibody and the adverse reaction of blood transfusion increase，the kinds of antibodies also increase. The times of blood transfusion shall be controlled in order to ensure the better effect of blood transfusion.
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