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The Clinical Effects of Advanced Cervical Carcinoma by Nedaplatin Combine with ConcurrentChemoradiotherapy |
Anshan City Tumor Hospital( Anshan City, the Fourth Hospital), Anshan 114036,China |
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Abstract Objective: To explore the clinical effects of advanced cervical carcinoma by nedaplatin combinewith concurrent chemoradiotherapy. Method: 135 cases of patients with advanced cervical carcinoma were randomlydivided into group A, group B and group C,45 cases in each group. The group A was treated by nedaplatin combinewith concurrent chemoradiotherapy, the group B was treated by cisplatin combine with concurrent chemoradiotherapy,the group C was treated by radiation. The clinical effects and adverse reactions were compared. Result: There was nosignificant difference on the total effective rate for group A and group B(P>0.05). The total effective rate for groupA and group B were higher than group C, the difference was statistically significant(P<0.05). The rate of adversereactions of I~IV for the group A were lower than the group B,the difference was statistically significant( P<0.05).The rate of adverse reactions of I for the group A were lower than the group B,the difference was statistically significant(P<0.05). Conclusion: The clinical effects of advanced cervical carcinoma by nedaplatin combine with concurrentchemoradiotherapy is good, it has high clinical effects, with low adverse reactions. It is worthy of clinical promotion.
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