|
|
|
| Clinical Analysis of 23 Cases with Neurosyphilis |
| The No.2 People’s Hospital of Yangzhou，Yangzhou 225001，China |
|
|
|
|
Abstract Objective：To analyze the clinical features， laboratory examination，imaging characteristics and diagnosis method of neurosyphilis.Method：23 patients with neurosyphilis were selected in No.1 People’s Hospital of Yangzhou from May 2009 to April 2015，the clinical features，laboratory examination， imaging characteristics，diagnosis and treatment of neurosyphilis were retrospectively analyzed.Result：The serum RPR and TPPA of all patients were positive，21 patients were positive with cerebrospinal fluid RPR and TPPA， 6 cases of cerebrospinal cell count increased，12 cases of the cerebrospinal fluid protein increased，the cerebrospinal fluid protein and white cell count was nomal had 5 cases.Among the 23 patients， 6 patients suffered dementia，11 cases suffered cerebral apoplexy，2 cases were neuralgia， 2 cases were epilepsy， 1 case was optic neuritis and 1 case was ataxia. The patients were no specifity MRI scanning，part of them showed cerebral infarctions，encephalatrophy，ventriculomegaly， varying degrees of cerebral white matter degeneration， gummatous abnormal signal or gyri enhancement and so on. Most of the patients showed obvious improvement in the symptoms after treated with penicillin or ceftriaxone.Conclusion： Neurosyphilis clinical manifestations are diverse and complex， part of them hidden but harm， combined with blood science，cerebrospinal fluid， and imaging examination are helpful to clinical diagnosis， timely and reasonable anti syphilis treatment can improve the prognosis.
|
|
|
|
|
|
|
|
|
