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| Effect of Ultrasound-guided Ultra-fine Percutaneous Nephrolithotomy in the Treatment of Lower Calyceal Calculus |
| LI Cunjie, ZHANG Haizhou, SUN Cheng, XIANG Huaijin, CAO Xiaopeng, LI Yanfeng |
| Wuxi Second Geriatric Hospital, Jiangsu Province, Wuxi 214174, China |
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Abstract Objective: To investigate the effect of ultrasound-guided ultra-fine percutaneous nephrolithotomy in the treatment of lower calyceal calculus. Method: A total of 80 patients with lower calyceal calculi who were admitted to the Wuxi Second Geriatric Hospital from November 2019 to October 2022 were selected and divided into an observation group (n=40) and a control group (n=40) according to the random number table method. The control group was treated with ultrasound-guided conventional percutaneous nephrolithotomy, and the observation group was treated with ultrasound-guided ultra-fine percutaneous nephrolithotomy. The operation-related indexes, renal function indexes, inflammatory factors indexes and the incidence of complications were compared between the two groups. Result: There were no significant differences between the two groups in the operation time and the first-stage stone clearance rate (P>0.05), and the hospitalization time of observation group was shorter than that of control group, hospitalization expenses was lower than that in the control group (P<0.05). Before operation, there were no statistically significant differences in the levels of serum creatinine (Scr), blood urea nitrogen (BUN) and neutrophil gelatinase-associated lipid transport protein (NGAL) between the two groups (P>0.05); after operation, Scr, BUN and NGAL in both groups increased, but those in the observation group were lower than those in the control group (P<0.05). Before operation, there were no significant differences in the levels of tumor necrosis factor-α (TNF-α), C reactive protein (CRP) and interleukin-6 (IL-6) between the two groups (P>0.05). After operation, all the above indexes in the two groups increased, but the observation group were lower than those in the control group (P<0.05). The incidence of complications in the observation group (2.50%) was lower than that in the control group (27.50%) (P<0.05). Conclusion: Ultrasound-guided ultra-fine percutaneous nephrolithotomy is safe and effective in the treatment of lower calyceal calculi, which can reduce renal function damage, inflammatory reaction and postoperative complications.
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Received: 30 January 2023
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