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| Etiological Characteristics and Risk Factors of Patients with Intracranial Infection Complicated with Pulmonary Infection after Craniocerebral Injury |
| XU Xi |
| The Second Affiliated Hospital of Shenyang Medical College, Shenyang 110002, China |
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Abstract Objective: To study the etiological characteristics and risk factors of patients with intracranial infection complicated with pulmonary infection after craniocerebral injury. Method: The Clinical data of 236 patients with intracranial infection with craniocerebral injury admitted to the Second Affiliated Hospital of Shenyang Medical College from February 2019 to February 2022 were retrospectively analyzed, and they were divided into infected group (59 cases) and non-infected group (177 cases) according to whether they were complicated with pulmonary infection. The composition of pathogenic bacteria in the infection group was analyzed, and the baseline data of the two groups were compared. Multivariate logistic regression was used to analyze the influencing factors of intracranial infection complicated with pulmonary infection after craniocerebral injury. Result: 67 strains of pathogenic bacteria were obtained by bacterial culture from 59 patients with craniocerebral injury complicated with intracranial infection, and Gram-negative bacteria and Gram-positive bacteria were dominant. In order of proportion from high to low, they were Acinetobacter baumannii, Klebsiella pneumoniae, Pseudomonas aeruginosa, Staphylococcus aureus, Staphylococcus haemolyticus and Escherichia coli, respectively, the proportions were 31.34%, 22.39%, 16.42%, 13.43%, 8.96% and 7.46%, respectively. The age of the infected group was higher than that of the non-infected group, the complications were more than that of the non-infected group, and the duration of coma and hospitalization were longer than those of the non-infected group, the proportion of smoking, open injury and multiple injury of infected group were higher than those of non-infected group (P<0.05). Multivariate logistic regression analysis showed that smoking, open injury, multiple injury, older age, more complications, long coma time and long hospitalization were risk factors of craniocerebral injury with intracranial infection complicated with pulmonary infection (P<0.05). Conclusion: Gram-negative bacteria and Gram-positive bacteria are the main pathogenic bacteria in patients with intracranial infection complicated with pulmonary infection after craniocerebral injury, the risk factors include smoking, open injury, multiple injury, age, comorbidity, coma time and hospitalization.
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Received: 22 September 2022
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