|
|
|
| Application of Dexmedetomidine Preoperative Nasal Drip Combined with Combined Intravenous and General Anesthesia in Laparoscopic Hernia Surgery in Children |
| ZONG Si, ZENG Weifu, ZHAO Jianshu |
| First-author's address: Jiujiang Maternal and Child Health Hospital, Jiangxi Province, Jiujiang 332000, China |
|
|
|
|
Abstract Objective: To analyze the practical application effect of Dexmedetomidine preoperative nasal drip combined with combined intravenous and general anesthesia in laparoscopic hernia surgery in children. Method: A total of 100 children with oblique inguinal hernia who underwent surgical treatment in Jiujiang Maternal and Child Health Hospital from April 2020 to April 2022 were selected and divided into two groups according to the random number table method, 50 cases in each group. The control group was given combined intravenous and general anesthesia. On the basis of this, the observation group was given Dexmedetomidine preoperative nasal drip. The anesthesia effect, analgesic effect, stress response, the incidence of negative postoperative behavioral changes (NPOBC) and adverse reactions were compared between the two groups. Result: The extubation time [(6.03±1.18) min], anesthesia awakening time [(18.31±1.53) min] and residence time in the anesthesia recovery room [(60.53±5.28) min] in the observation group were shorter than those in the control group [(9.43±1.69), (27.58±2.67) , (83.69±7.31) min], the differences were statistically significant (P<0.05). The visual analogue scale (VAS) scores of the observation group 15 min after wakefulness after surgery and 24 h after surgery [(3.25±0.97), (1.53±0.42) scores] were lower than those of the control group [(4.61±1.06), (2.31±0.65) scores], the differences were statistically significant (P<0.05). 24 h after surgery, the cortisol (Cor), norepinephrine (NE) and epinephrine (E) in the observation group were lower than those in the control group, the differences were statistically significant (P<0.05). 1 day after surgery, the incidence of NPOBC in the observation group was lower than that in the control group, the differences was statistically significant (P<0.05). There was no significant difference in the incidence of adverse reactions between the two groups (P>0.05). Conclusion: Dexmedetomidine preoperative nasal drip combined with combined intravenous and general anesthesia is effective in laparoscopic hernia surgery in children, with strong anesthetic and analgesic effects, which can effectively reduce the stress response of children and reduce the incidence of NPOBC without serious adverse reactions.
|
|
Received: 23 December 2022
|
|
|
|
|
|
|
