Objective：To observe the clinical effect of self-made Xuefu Gualou soup in the treatment of Coronary heart disease and unsteady type angina pectoris.Method：62 patients with unstable angina pectoris were randomly divided into western medicine group and observation group. The western medicine group do the guidelines and is given
standardized treatments， which conclude antiplatelet， anticoagulation， nitrates drugs， beta blockers， calcium antagonists and angiotensin converting enzyme inhibitor（ ACEI） or ARB， lipid regulating drugs， hypoglycemic agents etc. The observation group was cured with the western medicine plus the use of self-made Xuefu Gualou soup， then to determine the efficacy after 10 treatment days.Result：The observation group is greatly improved in the symptoms of angina pectoris，
electrocardiogram， pain attack frequency， nitroglycerin dosage etc， and the curative effect was better than western medicine group.Conclusion：On the basis of western medicine standardized treatment combined with Xuefu Gualou soup，there is a better curative effect than the pure western medicine treatment in improving patients with unstable angina pectoris symptoms and related indexes， and the safety is good and no obvious adverse reaction.