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| Histopathology and Histochemistry Changes of Amnion and Placenta with Oligohydramnios in Full Term Pregnancy |
| Tai’an Maternal and Child Care Hospital， Tai’an 271000， China |
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Abstract Objective：To explore the histopathologic and histochemistic changes of amniotic membrane and placenta with oligohydramnios in term pregnancy.Method：Amniotic membrane and placenta with normal amount amniotic fluid and oligohydramnios 15 cases in each group.The martial undergone fixation with 10% formaldehyde and routine paraffin section， HE staining and AB-PAS reaction.The slices were observed under light microscope and some index of the morphomatry acquired.Result：The amniotic cells of oligohydramnios became shriek and vesicle， even stratified metaplasia， PAS granules were reduced in their cytoplasm.Syncytail knots increased.AB-PAS reaction became weaken because of glycogen granules in cytoplasm were rare， the basement membrane of the capillaries at the villi became vary thinker， all these changes point on aging and disfunction.Conclusion：The histopathologic changes and glycogen reduce in amniotic cells， and number of syncytail knot raise， thinker vasculosyncytial membrane and rare glycogen et al in placenta villi take part in the pathological and physiological process of the oligohydramnios.
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