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Abstract Objective: To explore the relationship between carotid artery low-density plaque and recurrent cerebrovascular events in patients with acute cerebral infarction of carotid artery stenosis based on CT angiography. Method: A total of 86 acute cerebral infarction patients with carotid artery stenosis and low-density plaque confirmed by color ultrasound were selected from May 2020 to May 2021 in Nanchang Hongdu Hospital of TCM. All patients underwent CT angiography and were followed up for 1 year. The relationship between the general clinical data, bad habits, comorbidities, carotid artery low-density plaque information and recurrent cerebrovascular events were analyzed. The influencing factors of early recurrent cerebrovascular events were analyzed by multivariate logistic regression. Result: During 1 year follow up, 26 cases (30.23%) had recurrent cerebrovascular events were set up as the recurrent group, while 60 cases (69.77%) had no recurrent cerebrovascular events were set up as the non-recurrent group. The results of single factor analysis showed that there were statistically significant differences in hypertension, diabetes mellitus, degree of vascular stenosis, plaque length, plaque load, degree of plaque enhancement and intra-plaque bleeding between the two groups (P<0.05). Multivariate logistic regression analysis showed that plaque length [OR=6.630, 95%CI (1.720, 25.575), P=0.006], plaque load [OR=2.748, 95%CI (1.357, 5.568), P=0.005] and plaque enhancement grade 2 [OR=3.271, 95%CI (1.215, 8.804), P=0.019] were independent risk factors of recurrent cerebrovascular events. ROC curve results showed that the combined three risk factors of AUC was 0.965, 95%CI (0.931, 0.999), sensitivity was 100%, specificity was 80.00%. Conclusion: The length, load of carotid artery plaque and plaque enhancement grade 2 are independent risk factors of recurrent cerebrovascular events, CT angiography to observe the characteristics of carotid plaque in patients is of great value in evaluating the incidence of recurrent cerebrovascular events.
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Received: 04 January 2023
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