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Abstract Mild traumatic brain injury (mTBI), commonly known as concussion, is one of the most common neurological disorders, and the mechanisms of brain dysfunction remain unclear. At present, the diagnosis of mTBI depends largely on patients' subjective clinical symptoms, which are often unreliable and/or non-specific. The application of functional magnetic resonance imaging (fMRI) in the evaluation of mTBI makes up for the limitations of traditional structural imaging in the imaging diagnosis of mTBI, provides an objective imaging basis, and makes it possible to understand the interaction between neural network and brain regions in the pathogenesis of mTBI. Task-based fMRI and resting-state fMRI can deeply understand the neuropathological changes after mTBI from different angles, which can more accurately locate the damaged brain functional area, so as to comprehensively evaluate the severity of traumatic brain injury, greatly improve the accuracy of early diagnosis of mTBI, and play an important role in prognosis assessment.
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Received: 17 January 2023
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