Abstract Objective：To study the diagnosis value of ischemia modified albumin（IMA） in the acute coronary syndrome（ACS）.Method：50 ACS patients admitted to our hospital were selected in our study from 2011 to 2012. 50 healthy volunteers formed the control group. IMA， CK-MB were detected on their admission， then analyzed statistically. Result：IMA comparative difference of the case group and the control group was statistically significant（ P<0.001）. IMA was significantly raised in ischemia patients， compared with the ischemic group， the difference was statistically significant （P<0.001）， with an OR of 16.35（ 6.24-46.21）. CK-MB showed an OR of 2.13（1.12-6.11）. Sensitivity and specificity of IMA for the detection of ACS was 78% and 85% ， and CK-MB was 56% and 61%.The area under the ROC curve of IMA was 0.831 for ischemic v/s non-ischemic patients.Conclusion：IMA appears to be developing into a good and very potent marker of cardiac ischemia.
