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The Characteristics and Drug Resistance of Pathogenic Bacteria in Operative Incision Infection of Patients in Orthopedics |
Traditional Chinese Medicine Hospital in Huidong County, Huidong 516300,China |
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Abstract Objective: To analyze the characteristics and drug resistance of pathogenic bacteria in operative incision infection of orthopedics patients, to provide reference of controlling the operation incision infection incidence in department of orthopedics and clinical rational drug use. Method: 300 incision infectious patients as the research objects in department of orthopedics in our hospital from August 2011 to October 2014, were collected the surgical incision infection specimens, isolated pathogenic bacteria, using automatic analyzer in detection of bacterial pathogens and analysis of drug resistance. Result: 300 cases with a total of 920 strains of pathogenic bacteria cultured in department of orthopedics, patients with surgical incision infection and pus secretion specimen source: 818 strains accounted for 88.9%,33 from blood, accounted for 3.6%, drainage of 32 strains, accounted for 3.5%, 27 cases of joint effusion, accounted for 2.9%, other 10 strains, accounted for 1.1%. 920 strains of pathogenic bacteria, 597 strains of gram negative bacilli,accounted for 64.9%; 171 strains of gram positive coccus, accounted for 18.6%; 152 strains of fungi, accounted for 16.5%; incision infection in department of orthopedics was mainly pathogenic bacteria of gram negative bacilli, which pseudomonas aeruginosa ranked first, accounting for 32.6%, followed by Acinetobacter baumannii, accounted for 13%.Gram positive coccus was the second pathogens caused operation incision in department of orthopedics infection, including Staphylococcus aureus was the leading pathogen infection, accounted for 12.4%. The fungus was the third bacteria caused operation incision infection in department of orthopedics, which infected with Candida albicans, accounted for 7.8%; gram negative bacilli had higher rate to Amikacin, aztreonam, Pi La Shilling, cefepime, ticarcillin, resistant to levofloxacin, cefazolin, gram positive coccus had high resistance rate on the left ofloxacin, cefoxitin, penicillin,clindamycin. Conclusion: In application of antibiotic therapy in department of orthopedics must strictly according to pathogenic bacteria detection results, to determine the clinical medication types according to the result of drug sensitivity test, launch targeted, individual treatment, in order to optimize the anti infection treatment effect, reduce the incidence of postoperative infection.
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