Abstract Objective：To analyze and observe patients with chronic obstructive pulmonary ary disease（ COPD） exacerbation of emphysema phenotype of clinical features.Method：98 COPD patients were selected from July 2012 to April 2013， and check corresponding HRCT， visual grading method based on HRCT findings and combined with emphysema（ or references） the patients were divided into two groups， one score in patients within 0-8 points were
divided into a group， as a group without emphysema， scores in patients within 8-24 points are divided into a group， a set of emphysema. the clinical data of two groups of patients were collected and analyzed and compared.Result： Two groups of patients in the gender composition， arterial blood oxygen partial pressure（ PaO2） and forced expiratory volume in 1 second（ FEV1） expected % percentage had no significant difference（P>0.05）. Two groups of patients for age， body mass， arterial blood CO2 partial pressure（ PaCO2） and forced expiratory volume in 1 second（ FEV1）/forced vital capacity （FVC） had significant differences（ P<0.05）.Conclusion：COPD patients with emphysema may reflect the severity of the
disease， also provide the basis for the treatment of COPD.
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