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Surgical Treatment and Diagnosis of Differentiated Thyroid Carcinoma: An Analysis of 76 Cases |
The Affiliated Hospital of Medical College of Jiaying University, Meizhou 514031,China |
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Abstract Objective: To investigate the diagnosis and surgical selection in differentiated thyroid carcinoma.
Method: Clinical data of 76 differentiated thyroid carcinomas were analyzed retrospectively from January 2010 to December 2013. 18 cases were carcinoma with nodular goiter, 5 cases were carcinoma with thyroid adenoma,3 cases were carcinoma with hashimoto thyroiditis, 1 case was carcinoma with hyperthyroidism. Result: 68 patients( 89.47%) were diagnosed according to intraoperative fast frozen section. 69 cases( 90.79%) were approved papillary thyroid carcinoma,7 cases( 9.21%) were follicular thyroid carcinoma. Especially inside of diolame invasion in 13 patients( 17.11%) and outside of diolame invasion in 9 patients( 11.84%). Neck dissection was performed in 64 patients, and 47 of them(61.83%) had cervical lymph node metastasis. The various styles of thyroidectomy were performed, 7 cases showed temporary vocal cord paralysis, 2 cases showed permanent after operation; 7 cases had convulsion or limbs numbness due to hypocalcemia, and 5 cases had thyroid function decrease. Follow up of all cases showed local recurrence in 12 patients,cervical lymph node recurrence in 5 patients and distant metastasis in 3 patients. Conclusion: Intraoperative fast frozen section is helpful for the diagnosis and the choice of operation method. The various surgical selection of thyroidectomy are performed according to the different pathological types, tumor type,pathological changes scope,age and cervical lymph node metastasis.
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