Abstract Objective:To explore the value of myoglobin in early diagnosis of myocardial infarction-induced coronary heart disease.Method:The myoglobin concentration of 310 patients with coronary heart disease was determined by immune turbidimetry,including 130 patients with myocardial infarction-induced coronary heart disease hospitalized during acute phase,80 cases patients with unstable angina and 100 patients with coronary heart disease of nonmyocardial infarction.Result:The peak value of 48 patients undergoing coronary artery recanalization( 45.0±18.2)min with average value at( 888.7±47.0)μg/L(P<0.05),average myoglobin before treatment hit( 534.3±197.6)μg/L,and the statistical difference was remarkably significance(P<0.05).Myoglobin abnormalities continued( 37.8±6.3) h. The attack period and intermittent period in patients with unstable angina of myoglobin hit( 55.8±21.4)μg/L and(40.9±12.0)μg/L respectively,the comparative self difference was statistically significant(P<0.01) before the start of activity,the myoglobin concentration of 100 patients with myocardial infarction-induced coronary heart disease group hit( 33.8±12.0)μg/L,and that value hit( 45.8±20.9)μg/L,the comparative difference before and after activity was statistically significant(P<0.01).Comparative differences in myoglobin between instable angina group,exercise group and myocardial infarction group of coronary heart disease were statistically significant(P<0.05).Conclusion:The myoglobin is an effective diagnosis biochemical index of myocardial infarction-induced coronary heart disease in acute period,and it contributes to the identification of unstable angina,strict control over clinical indexes including the hypertension,high cholesterol and cerebral apoplexy type,being contributable to the prevention and treatment of myocardial infarctioninduced coronary heart disease and unstable angina.
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