Abstract Objective：To analyze clinical characteristics of children lobar pneumonia combined with mycoplasma pneumoniae infection，and offer the basis for the diagnosis of illness.Method：120 cases of mycoplasma pneumoniae infection hospitalized from August 2012 to August 2014 who were selected as study objects，there were 55 cases of bronchial pneumonia，who were selected as control group，there were 65 cases of lobar pneumonia combined with mycoplasma pneumoniae infection，who were selected as the observation group，age，pneumonia show，complications，treatment and prognosis of performance of children patients of two groups were compared.Result：Illness age incidence of children patients of the observation group were from five to twelve，fever（above 38.5 ℃），gastrointestinal symptoms，psychiatric symptoms，liver and cardiac damage，pleural effusion and pulmonary atelectasis complications were respectively 84.62%，24.62%，20.00%，52.31%，27.69%，those of the control group were 54.55%，9.09%，3.64%，23.64%，7.27%，the differences had statistical significance（P<0.05）.X-ray absorption rates of two weeks of the observation group were significantly less than those of the control group（P<0.05），average hospitalization time of other two groups were[（18.20±3.58）d vs（12.08±1.85）d]，the difference had statistical significances （P<0.05）.Conclusion：Lobar pneumonia with pneumonia mycoplasma infection is main school aged children，easily combined
with pulmonary complications，course of treatment is long and chest X-ray absorption is relatively slow.
