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Abstract Objective：To assess the relationship between optic nerve sheath diameter（ ONSD） measured on bedside ultrasound（ US） and simultaneously measured intracranial pressure（ ICP） in patients.To explore the the clinical application of ONSD in the intracranial hypertension patients after surgery.Method：Twenty-six brain disease patients were included in this study，contained 15 patients with heavy brain injured patients，6 large area cerebral infarction and 5 brain tumor.The Sonosite color Doppler US was used to measure ONSD on bedside postoperation in the first，second and third days.and monitoring vital signs and GCS score，survival rate.To statistically analyze all data.Result：The average postoperative ONSD <5 mm of the brain disease patients after surgery were 17 cases，>5 mm were 6 cases，>6 mm were 6 cases，the death were 7 cases，the plant survival were 2 cases.Conclusion：These data suggest that dynamic monitoring of ONSD changes after craniocerebral operation was helped to correctly judge patients after craniocerebral operation condition changes，Guidance and timely recheck CT or reoperation，can become a routine means of neurological Intensive Care Units.
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