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Discussion of the Relationship of Immune T Cell Function and Serum Cortisol in Children with Recurrent Respiratory Infections |
Guangzhou Yuexiu Children’s Hospital,Guangzhou 510115,China |
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Abstract Objective:To study the relationship of immune T cell function and serum cortisol in children with recurrent respiratory tract infection.Method:20 children with recurrent respiratory tract infections in our hospital from June 2013 to November 2014 were selected as the treatment group,20 cases of healthy children were selected as a control group.Used flow cytometry,ECL method in the treatment group,children with the disease progression,disease stabilization period( four weeks after respiratory symptoms disappear),healthy children,T cells were detected in the serum levels of serum cortisol( COR) of content changes,T cell immune function and serum cortisol relationship were compared and analyzed.Result:RRTI children with recurrent respiratory tract infection,stable disease due to T cell CD3+,CD4+ secretion of a large number of children with accessibility in vivo serum COR indicators of normal children,but when the disease progresses,the body as a result of children with T cells secrete CD3+,CD4+ reduced,resulted in lower levels in vivo serum COR.Conclusion:Children with recurrent respiratory tract infection of T cells in vivo serum levels of serum cortisol( COR) to monitor changes in content,RRTI understand the etiology and pathogenesis,a key factor in reducing the incidence and reduce the number of children with recurrent respiratory tract infections,and help clinical treatment,prognosis and reduce disease progression,reduce the heavy economic burden on patients and government high medical costs.
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