Objective： To observe the effect of Otilonium bromide combined with Oxalic acid Ai Sciplan in the treatment of irritable bowel syndrome（IBS）. Method： 60 cases with irritable bowel syndrome were selected according to the Rome Ⅲ diagnosis criteria， they were grouped by the visit order of odd and even， odd as the research group， even for the control group， 30 cases in each group. Before entering the group ，they were score by irritable bowel syndrome severity scale（IBS-SSS）， when enrolled the two groups were given otilonium bromide 40 mg，tid， the research group in conjunction with oxalic acid Ai Sciplan 10 mg/d within 12 weeks. After 12 weeks， the research group continues taking escitalopram oxalate to 24 weeks， the two groups used otilonium bromide according to abdominal pain duringon-demand during 12 to 24 weeks（not as a conventional take）. Result： The treatment effect was evaluated respectively at the end of 2， 4， 8， 12， 24 weeks， and the IBS-SSS scores of the research group were（185.00±38.24），（149.07±38.30），（127.83±37.51），（112.97±37.55），（102.97±43.82）， the control group scores were（226.80±42.98），（183.33±41.90），（165.33±37.19），（152.30±39.41），（147.57±41.46）， followed by the two groups， the control group scores were significantly different（P<0.01）. Conclusion： Joint use of escitalopram oxalate and otilonium bromide can ease patients abdominal pain， abdominal discomfort and abnormal bowel movements， improve the quality of life of patients at the same time. This method has lasting efficacy，safety，well tolerated，and small relapse risk when sustained drug use.

2015 Vol. 12　(1):　1-3 [Abstract]（ 754 ） HTML (1 KB)  PDF  (998 KB)  ( 416 )

Objective：　The expression and significance of serum soluble intercellular adhesion molecule-1 in children with influenza A virus pneumonia and respiratory syncytial virus pneumonia in -1， in order to guide the clinical treatment and prevention. Method： In our hospital from pneumonia in children， according to the reverse transcriptase polymerase chain reaction results were divided into FA group（ A influenza virus positive） 36 cases， group RSV（ respiratory syncytial virus positive） in 22 cases， at the same time in healthy children at our hospital physical examination 41 cases as control group，serum sICAM-1 were compared between the three groups children’s value. Result： In FA group and RSV group， serum sICAM-1 values were higher than those in the control group， there was significant difference（ P<0.05）.Conclusion： The expression of A increased the level of sICAM-1 influenza virus pneumonia and respiratory syncytial virus pneumonia in children， which is one of the important inflammatory airway inflammation in children， can provide clinical treatment with anti adhesion therapy and anti-inflammatory， inhibiting inflammatory factors to provide evidence.

2015 Vol. 12　(1):　7-9 [Abstract]（ 601 ） HTML (1 KB)  PDF  (1238 KB)  ( 416 )

Objective： To investigate the diagnosis and surgical selection in differentiated thyroid carcinoma. Method： Clinical data of 76 differentiated thyroid carcinomas were analyzed retrospectively from January 2010 to December 2013. 18 cases were carcinoma with nodular goiter， 5 cases were carcinoma with thyroid adenoma，3 cases were carcinoma with hashimoto thyroiditis， 1 case was carcinoma with hyperthyroidism. Result： 68 patients（ 89.47%） were diagnosed according to intraoperative fast frozen section. 69 cases（ 90.79%） were approved papillary thyroid carcinoma，7 cases（ 9.21%） were follicular thyroid carcinoma. Especially inside of diolame invasion in 13 patients（ 17.11%） and outside of diolame invasion in 9 patients（ 11.84%）. Neck dissection was performed in 64 patients， and 47 of them（61.83%） had cervical lymph node metastasis. The various styles of thyroidectomy were performed， 7 cases showed temporary vocal cord paralysis， 2 cases showed permanent after operation； 7 cases had convulsion or limbs numbness due to hypocalcemia， and 5 cases had thyroid function decrease. Follow up of all cases showed local recurrence in 12 patients，cervical lymph node recurrence in 5 patients and distant metastasis in 3 patients. Conclusion： Intraoperative fast frozen section is helpful for the diagnosis and the choice of operation method. The various surgical selection of thyroidectomy are performed according to the different pathological types， tumor type，pathological changes scope，age and cervical lymph node metastasis.

2015 Vol. 12　(1):　14-16 [Abstract]（ 579 ） HTML (1 KB)  PDF  (997 KB)  ( 223 )

Objective： To investigate the risk of bleeding esophageal varices and clinical studies related surgical options of Cirrhosis. Method： To choose subjects bleeding esophageal varices in 151 patients with cirrhosis， respectively transjugular shunt 52 cases of intrahepatic portal chamber， endoscopic band ligation 48 cases， selective cardia from around 51 cases of vascular surgery off， observe and compare three groups preoperative and postoperative January，March portal venous pressure measurements recorded follow-up of patients re-bleeding， bleeding after treatment and hospitalization expenses. Result： After the treatment of three patients of improvement inportal pressure， surgical operation group was significantly better than the other two groups， the difference was statistically significant（ P<0.05）. And the surgical operation group the rate of rebleeding and second bleeding time was significantly better than the other two groups，which had significant difference（ P<0.05）. Conclusion： Simple shunt and endoscopic of cirrhosis with esophageal and gastric fundus varices in patients of the treatment effect is not obvious， and control patients are not well rebleeding cases.Selective pericardial devascularization around blood vessels can fundamentally improve the portal venous pressure in patients with high， worth in clinical application.

2015 Vol. 12　(1):　20-22 [Abstract]（ 504 ） HTML (1 KB)  PDF  (996 KB)  ( 481 )

Objective： To observe and research the impacts of vaginal secretions on urine routine test results and put forward the corresponding treatment strategies and means. Method： From November 2011 to November 2013， 120 female patients， who were examined and diagnosed as having gynecological diseases， were selected from Nanyang Central Hospital as the objects of this study. According to the random number method， those patients were divided into two groups，namely control group and observation group， with 50 cases and 70 cases respectively. For the control group， conventional urine collection method was used before the urine routine test， while the observation group， under the guidance of primary nurses， carried out the urine collecting checks after preventing vaginal secretions out. Then， comparative observation of urine collection and test results of the two groups were carried out. Result：（ 1） In the control group， detection rate of leukocytes was 46.00%， and detection rate of erythrocytes was 90.00%. In observation group， detection rate of leukocytes was 5.71%， and detection rate of erythrocytes was 28.57%. The detection rates of leukocytes and erythrocytes in the patients of control group were significantly higher than those in the patients of observation group， and differences between the two groups were significant（ P<0.05）（. 2） In observation group， epithelial cell and protein detection rates in patients’ Urine specimens are both zero， while in the control group， the detection rates of epithelial cells and protein were 4.00% and 22.00% respectively. The detection rates of epithelial cell and protein in the patients of control group were significantly higher than those in the patients of observation group， and differences between groups comparison were significant，（P<0.05）. Conclusion： Vaginal secretions have varying degrees of impact on the results of routine urine test， leading to false-positive detection rate increased. To further improve the accuracy of urinalysis， it is necessary to strictly follow the standard operation in the urine sample collection， and strengthen collection training of related physicians， so that to improve the qualification rate of urine collection and improve the accuracy of diagnosis.

2015 Vol. 12　(1):　26-28 [Abstract]（ 638 ） HTML (1 KB)  PDF  (1020 KB)  ( 364 )

Objective： To observe the clinical effect alpha1-antitrypsin（ α1-AT） and serum C reactive protein （CRP） levels in patients with acute exacerbation chronic obstructive pulmonary disease（ COPD）. Method： 64 patients with AECOPD in our hospital were chosen and divided randomly to observation group and control group， which all treated by basis treatment and pulverization inhalation treatment with salbutamol and ipratropium bromide. Patients in observation group were also given pulverization inhalation treatment of budesonide. The levels of serum CRP and α1-AT were compared after seven days treatment， and the clinical effects were evaluated and compared. Result： The CRP level of the AECOPD group was significantly higher than that of the stable COPD group（ P<0.05）， but the α1-AT level had no obviously differences between the two group（ P>0.05）. The levels of serum CRP and α1-AT significantly decreased after treatment， and the CRP level was significantly lower in observation group than that in the control group（ P<0.05）， while the α1-AT level between the two groups had no statistically significant differences（ P>0.05）. Conclusion： CRP is a sensitive indicator for the patients with COPD， combing with α1-AT associated detection， have clinical practical value for diagnose and therapeutic effect judging in COPD.

2015 Vol. 12　(1):　32-34 [Abstract]（ 492 ） HTML (1 KB)  PDF  (998 KB)  ( 215 )

Objective： To analyze related factors affected the degree of depression after stroke and treatment of patients with varying degrees of depression by clinical investigation of 102 cases of depressions after stroke.Method：102 cases of depressions after stroke of age， sex， occupation， family relationships， frequency of stroke，comorbidities（including hypertension， diabetes， coronary heart disease， etc.） were to investigated ， related factors of the degree of depression were explored by the application of Logistic regression，while applications of depression self-assessment form and Hamilton Depression table for 102 patients with the degree of depression were evaluated，then 58 cases of mild depression， moderate to severe depression were 44 cases. The mild and moderate to severe depression who were divided into two groups，29 cases in each mild depression groups and 22 cases in each moderate to severe depression groups.The experimental group of patients with psychological therapy and fluoxetine combination therapy，and the control group were treated with psychotherapy alone. After treatment， social support tables， stroke patients of quality of life assessment form and Hamilton Depression Scale for efficacy evaluation were used.Result： Age， family relations， and the number of stroke，complications were related factors affecting the degree of depression after stroke， there was statistical significance；for patients with mild depression，effect was good， clinical efficacy between the experimental and control groups was no significant differences； for patients with moderate to severe depression， the clinical efficacy of the experimental group was significantly higher，there was a statistically significant difference（P<0.05）. Conclusion： Age， family relations，and the number of stroke， complications are related factors that affects the degree of depression after stroke， for patients with mild depression， psychotherapy alone can achieve better results， for patients with moderate to severe depression， the clinical efficacy of psychological therapy combined with fluoxetine is better than psychotherapy alone.

2015 Vol. 12　(1):　38-40 [Abstract]（ 596 ） HTML (1 KB)  PDF  (997 KB)  ( 222 )

Objective： To observe or explore density change of fluid internal ventricle and big arteriovenous vessel by CT value measured. Method：（ 1） Retrospective analysis CT image data of 41 anemia patients， including 40 cases chest and 21 cases of abdominal CT inspection. To find normal chest CT 40 cases and abdominal CT 21 cases in PACS.respectively measured CT value of areas of interest（x±s）， and then make a comparison. Also calculate the ration of the left ventricle and the interventricular septum CT value or the ratio of the liver parenchyma and liver intravascular CT value in each group.（ 2） To Randomly select CT 20 cases of head and chest CT 40 example image data， measure venous sinus and double internal carotid artery CT value， inferior vena and thoracic aorta CT value. To compare density difference of arterial blood and venous blood.（ 3） In case of secondary erythrocytosis disease observation of CT image data， through the measurement of CT values of interest area， combining with the hemoglobin concentration， understand the cause of the CT value was higher than normal blood. Result：（ 1） CT value of all the interest in areas such as thoracic aorta， left and right ventricle the abdominal aorta in anemia group and normal control group. In corresponding points matching mean comparison， the difference was statistically significant（ P<0.01）. Anemia group， the left ventricle/ ventricular ：35%-87%；the portal vein/the liver parenchyma： 26%-48%. Normal control group， the left ventricle/ ventricular： 88%-100%；the portal vein/the liver parenchyma： 68%-82%. By comparing， the difference was statistically significant（ P<0.01）.（2） Measuring the interest area such as： internal carotid artery， venous sinus， inferior vena cava diaphragmatic upside segment and at the same level of the thoracic aorta. The area on behalf of arterial blood and venous blood was matching mean comparison（ P<0.01）.（ 3） In the case of secondary erythrocytosis disease of bilateral internal carotid artery，superior sagittal sinus， sigmoid sinus， left and right ventricle， chest aorta， double renal artery CT value measurement about 55-70 HU， hemoglobin concentration of 244-256 g/L. Conclusion： Anemia and blood cells increased disease can be diagnosed by CT value simple measurement. The reason of the venous sinus density slightly higher than brain parenchyma and the arterial blood except sinus blood stream is slow and high density of dura mater， venous blood density is higher than the arterial is also one of the reason.

2015 Vol. 12　(1):　43-46 [Abstract]（ 571 ） HTML (1 KB)  PDF  (1047 KB)  ( 271 )

Objective： To explore the best treatment of pelvic abscess， through the analysis of laparoscopic operation and CT guided percutaneous puncture drainage effect in the treatment of pelvic abscess. Method： Clinical data of 69 patients suffering from pelvic abscess were analyzed retrospectively. Among them， 38 patients were given laparoscopic surgery treatment. 31 cases were given percutaneous puncture drainage treatment， under the CT guidance. The treatment efficacy of the two groups was compared. Result： The operation time was significantly longer than the interventional operation treatment， and the volume of hemorrhage during operation between the two groups were significantly different（P<0.01）. The cure rate and effective rate were not statistically significant. The recurrence rate had significant difference（P<0.05）. Conclusion： Under the CT guidance， percutaneous puncture drainage is an ideal method for treatment of pelvic abscess. Interventional treatment of pelvic abscess is smaller than the laparoscopic operation trauma. Treatment is equivalent to laparoscopic operation. The recurrence rate is significantly lower than that in laparoscopic operation.

2015 Vol. 12　(1):　49-52 [Abstract]（ 540 ） HTML (1 KB)  PDF  (1054 KB)  ( 486 )

Objective： To investigate efficacy of long-term and low-dose Luo erythromycin combined with aminophylline in treatment of patients with bronchiectasis. Method： From March 2012 to March 2013 in our hospital 112 patients with bronchiectasis were randomly divided into control group and observation group，each contained 56 cases.The control group was treated by Luo erythromycin. On the basis of the control group，observation group was treated by aminophylline， additionally. Lung function， sputum volume， attack times， effectiveness were observed before and after 1 year of treatment. Result： Lung function， sputum volume， attack times of observation group were better than those of the control group after 1 year of treatment， with a statistically significant difference（ P<0.05）. The total efficiency of the observation group（ 95.4%） was better than that of the control group（ 76.4%）， with a statistically significant difference（P<0.05）. Conclusion： Long-term and low-dose Luo erythromycin combined with aminophylline in treatment of patients with bronchiectasis showed sastifying efficacy and worthy of introduction.

2015 Vol. 12　(1):　55-57 [Abstract]（ 558 ） HTML (1 KB)  PDF  (1003 KB)  ( 244 )

Objective： To study the relation between Intervertebral disc herniation and lumbosacral transitional vertebra on CT. Method： There were 135 patients with lumbosacral transitional vertebra， the type of lumbosacral transitional vertebra and the CT manifestations， the anatomy， type， form and severity of Intervertebral disc herniation were analyzed for all patients. Result： The incidence of Lumbar sacral was more than that of Sacral vertebra waist， lumbosacral transitional vertebra were prone to caused lumbar disk hernia in lumbar 4/5 clearance， many involving multiple intervertebral disc， dural sac and nerve root were compressed severely. Conclusion： Lumbosacral transitional vertebra easily lead to the occurrence of lumbar disc hernia， and the extent of the lesions occur heavier.

2015 Vol. 12　(1):　60-62 [Abstract]（ 587 ） HTML (1 KB)  PDF  (1338 KB)  ( 395 )

Objective： To evaluate the value of hepatic artery infusion pump chemotherapy for the prevention of liver metastasis after radical resection of colon cancer. Method： According to the different treatment methods， 33 cases without liver， lung， brain metastasis of distant organs in patients with colon cancer were randomly divided into treatment group and control group， the treatment group was treated with chemotherapy by hepatic artery infusion pump， while the control group underwent peripherally inserted central catheter chemotherapy， and the survival time without liver metastasis was compared. Result： In the treatment group， the average survival time without liver metastasis was（ 24.2±4.3）months， while in the control group， the average survival time without liver metastasis was（ 16.6±2.0） months. There were statistically significant differences between the two groups. The survival curves of the two groups by the endpoint of liver metastasis had statistically significant difference（ Log-Rank 字2=25.085，P=0.000）. Conclusion： Compared with the conventional intravenous chemotherapy， hepatic artery infusion pump chemotherapy after radical resection of colon cancer can effectively delay the liver metastasis after radical resection of colorectal cancer， and is a modus operandi for the prevention of liver metastases from colorectal cancer.

2015 Vol. 12　(1):　65-68 [Abstract]（ 519 ） HTML (1 KB)  PDF  (1159 KB)  ( 475 )

Objective： To investigate the effectiveness and safety of milrinone in treatment to refractory heart failure. Method： During January 2012 to June 2014， 60 patients with refractory heart failure were divided into sodium nitroprusside group（ n=30） and milrinone group（n=30）. The dosage of sodium nitroprusside and milrinone were 0.5-3 μg/（kg·min）min and 0.5 μg/（kg·min）， which the time of duration was 3 days. Result： 28 patients in sodium nitroprusside group and 25 patients in milrinone group were included in the analysis. 7-day effectiveness of the milrinone group was significantly higher than that of the sodium nitroprusside group（ P<0.05）. BNP of the milrinone group after treatment was significantly lower than that of the sodium nitroprusside group（ P<0.05）. There were significant differences in LVEF， E/A， SV， CI between the two groups（ P<0.05）. There was no significant difference in incidence of adverse events between the two groups. Conclusion： Milrinone can improve the success rate of rescue in patients with Refractory heart failure.

2015 Vol. 12　(1):　71-73 [Abstract]（ 753 ） HTML (1 KB)  PDF  (1001 KB)  ( 205 )

Objective： To discuss Ultrasound assessment of the artery endothelial function value and analyze the relationship with atherosclerosis. Method： 43 patients with coronary heart disease were selected from March 2008 to August 2012 in our Hospital as atherosclerosis group， at the same time to choose a medical section 43 cases normal adults as control group， all the patients received color Doppler ultrasound to arterial endothelial function in each parameter detection， to analyze the relationship endothelial function and the hardening of the arteries by Logistic Regression Analysis.Result： Atherosclerosis group with carotid artery plaque incidence， carotid artery， carotid artery - in the film thickness. was significantly higher than the control group， the difference was statistically significant（ P<0.05）. Atherosclerosis group endothelial diastolic ability significantly was lower than the control group patients（ P<0.05）. Logistic regression analysis results showed that， carotid of plaques， carotid artery-in the film thickness， endothelial diastolic ability was a risk factor for coronary atherosclerosis. Conclusion： Ultrasonic testing can effectively assess artery endothelial function， carotid of plaques， carotid artery-in the film thickness， endothelial diastolic ability has close relationship with coronary atherosclerosis， it’s expected to become the index of prognosis of atherosclerosis.

2015 Vol. 12　(1):　76-78 [Abstract]（ 580 ） HTML (1 KB)  PDF  (1022 KB)  ( 201 )

Objective： To analyze the ultrasonic bone mineral density testing results in different gender different in 3 months to 2 years old age group children， provide the basis for clinical prevention of children’s low bone mineral density.Method： Children were attended the outpatient clinic physical examination， and 230 children with 3 months to 2 years old who had been ruled out of bone metabolic diseases were selected. Middle tibia bone density was measured by ultrasonic bone mineral density instrument， according to the same gender， age， bone mineral density of Z value evaluation scores were divided into normal， mild， moderate， severe lack of bone strength. Result： Ji’nan area for 3 months to 2 years old children’s bone strength Z value was（ -0.0439±0.9324）. Bone strength was insufficient detection rate of 16.08%. Girls lack of bone strength detection rate（ 22.01%） was higher than boys（ 10.74%）， the difference was statistically significant（χ²=5.3998，P<0.05）. Different age groups lack of bone strength detection rate： <1 year group（ 31.76%）， 1 year old age group（ 9.87%）， 2 years old age group（ 3.12%）. 3 months - 1 year old age group children lack of bone strength detection rate was higher than 1 year group， the difference was statistically significant（χ²=11.9424，P<0.01）. 1 year old age group of inadequate bone strength detection rate and 2 groups compared with no statistical significance（ χ²=1.5955，P>0.05）. Conclusion： Ji’nan 3 months to 3 years old children’s lack of bone strength detection rate is different， where<1， the highest detection rate of the group， girls were highest， ultrasonic bone mineral density testing for guiding children calcium supplements and the prevention of infantile rickets.

2015 Vol. 12　(1):　82-84 [Abstract]（ 515 ） HTML (1 KB)  PDF  (1042 KB)  ( 290 )

Objective： To meet patient demand for health education in the perioperative period for post-natal treatment， care， outcomes， breastfeeding guidance fully prepared based on the overall care. Method： According to the physiological characteristics and recovery of puerperal women， the physiological characteristics， maternal postpartum recovery and the health education process， the use of slides and health education mission alone， for the period prior to surgery， during and after various stages of the mission. 46 cesarean patients in January 2013 were randomly divided into two groups， control group used the traditional clinical nursing method， the observation group received health education，nursing process method， comparing nursing effect of the two groups. Result： The observation group on maternal health knowledge level was higher than that of the control group， the satisfaction of nursing quality was higher than that of the control group， the differences were statistically significant（ P<0.05）. Conclusion： Cesarean section around the application of health education and nursing method is better than the traditional nursing operation period， and improve the quality of medical service and patient satisfaction.

2015 Vol. 12　(1):　88-90 [Abstract]（ 605 ） HTML (1 KB)  PDF  (996 KB)  ( 276 )

Objective： To through the discussion of the quality of nursing care and the traditional nursing for patients with diabetes mellitus perioperative blood glucose control and operation period of wound healing， nursing the people-oriented， and create a warm nursing culture， to improve the quality of nursing service. To achieve Three Satisfaction-patient satisfaction， social satisfaction， satisfaction of government. Method： From 2012 May to 2014 May in Department of orthopedics 56 diabetic patients undergoing Department of orthopedics operation treatment were divided into two groups. The control group used traditional nursing， research group with high quality nursing care. Compared two groups with operation during perioperative period before， during， and after the operation， the blood glucose level（ including 2 h blood glucose and fasting after meals）， urine， urine ketone body， there was no hypoglycemia， cardiovascular complications， time of anti inflammation and wound healing. Result： By comparing to controlling blood sugar of preoperation and postoperation， the study group had obviously fewer days than the control group. And postoperative would healing had fewer days than the control group. The satisfaction of the patients was higher than the control group.Conclusion： Patients with diabetes nurse on duty system， comprehensive， high quality nursing care can reduce hospitalization time， reduce or avoid complications， relieve patients with confusion， improve patient quality of life.

2015 Vol. 12　(1):　94-96 [Abstract]（ 568 ） HTML (1 KB)  PDF  (996 KB)  ( 367 )

Objective： To study the relationship of between depressive symptoms and occupational stress of the medical staff. Method： The differences of the gender， age， marital status， education level， job， night shift situation，weekly working hours， welfare satisfaction and doctor-patient relationship of 758 cases of medical staff were compared by questionnaire analysis. The relationship of medical staff between depressive symptoms and occupational stress was analyzed by Logistic regression analysis. Result： 422 cases among the 758 cases of medical staff showed depressive symptoms， and the detection rate of depressive symptoms was 55.67%. There were significant differences in medical staff among the age，marital status， position， the night shift， weekly working hours， welfare satisfaction and doctor-patient relationship by the single factor analysis， the differences were statistically significant（ P<0.05）. By Logistic regression analysis， there was a close correlation among high pay-high returns， low pay-low returns， high cost-low returns and depressive symptoms，the differences were statistically significant（ P<0.05）.The higher of the tension degree， and the release rate of depressive symptoms were the bigger. Conclusion： There were a close relationship in medical staff between depressive symptoms and occupational stress.Effective prevention and control measures formulated could obviously reduce the incidence rate of mental depression in medical staff，improve medical efficiency and reduce the occurrence of medical disputes cases.

2015 Vol. 12　(1):　100-102 [Abstract]（ 544 ） HTML (1 KB)  PDF  (995 KB)  ( 247 )

Objective： To observe and explore the clinical value of Xiaoqinglong Decoction（ XQLD） on lung function and serum cytokines in patients with acute exacerbation of Chronic obstructive pulmonary disease（ AECOPD）.Method： 96 patients with AECOPD in this hospital since June 2011 to May 2014 were selected， 96 patients were randomized divided into two groups， each group contained 48 cases， the observation group was treated with XQLD on the basis of conventional Western medicine treatment， while the control group was treated with conventional western medicine.Lung function including forced expiratory volume in one second（ FEV1）， forced vital capacity（ FVC） and peak expiratory flow（ PEF） in patients before and after treatment were measured， as well as interleukin -4（ IL-4）， interleukin-8（ IL-8）and tumor necrosis factor（ TNF-α） levels were monitored. Result： The difference of FEV1， FVC， PEF， IL-4， IL-8 and TNF-α before treatment between the two groups was not statistically significant（ P<0.05）， after treatment FEV1， FVC and PEF in the observation group was（ 1.28±0.38）L，（ 2.11±0.60）L and（ 3.12±1.29）L， and（ 1.18±0.28）L，（2.02±0.53）L and（ 2.83±1.02）L in the control group， the difference was statistically significant（ P<0.05）. After treatment， IL-4， IL-8 and TNF-α level in the observation group was significantly lower than that of the control group，the difference was statistically significant（ P<0.05）. The total efficiency of observation group was 91.7%（ 44/48）， and for the control group was 72.9%（ 35/48）， the difference was statistically significant（ P<0.05）. Conclusion： XQLD combined western medicine can significantly improve lung function in patients with AECOPD， relieve inflammation， with a significant effect， thus is a safe and effective therapy for patients with acute COPD.

2015 Vol. 12　(1):　109-111 [Abstract]（ 442 ） HTML (1 KB)  PDF  (999 KB)  ( 350 )

Objective：To investigate the distribution of common pathogenic bacteria and the condition of drug resistance with pediatric respiratory tract infection in Shenyang，for clinical diagnosis and treatment of children with timely to provide a basis. Method：The isolates were identified by API system and the antibiotic susceptibility test was detected using the K-B method for the sputum and blood of 1397 pathogens　cases pediatric respiratory tract infection were treated by Shenyang Children’s Hospital . Result：582 pathogens were detectined in 1397 cases sputum specimens，which G- bacilli 453 strains（ 77.8%）and G+ bacilli of 98 strains（16.8%），mixed infection of 15 strains（2.6%），13 strains of fungal infection（ 2.2%），3 strains of other bacteria. Conclusion：In this region，gram-negative bacilli is the major pathogensin in patients with pediatric respiratory tract infections， fungal infection rates is also on the rise. Antibiotics therapy should be made according to bacteriologic examination and antibiotic sensitivity test.

2015 Vol. 12　(1):　115-117 [Abstract]（ 432 ） HTML (1 KB)  PDF  (997 KB)  ( 213 )

Objective： To improve the confirmation percentage of ultrasonic diagnosis through analyzing the features of sonogram. Method：98 cases patients with the vaginal ultrasonography were selected by inspect the clinical suspected ectopic pregnancy， the uterus and its parametrium under different positions were scanned and the ultrasonogram of the uterine cavity as well as its parametrium were observed. Result： Among these cases， endometrial hyperplasia taked up 35.7 %；intrauterine pregnancy sac was 13.6%；the percent on behalf of the specificity blocks was 21.4； non-specificity blocks was the most largely percentage of 78.6%； truly describe the ratio of pelvic effusion was 63.4 %.Conclusion：Due to the following characteristic， such as the high correct detection probability ， vaginal ultrasonography is the best way to diagnose ectopic pregnancy. It can be confirmed via the specificity ultrasonogram. We can make an accuracy diagnose when studying the symptoms of non-specificity blocks，the history of menelipsis，irregular vaginal bleeding，abdominal pain，the positive pregnancy test and pelvic effusion. When patients exhibit the above clinical symptoms meanwhile the ultrasonic examination shows negative or non-typical sonograms， we should not give up any considerations of ectopic pregnancy instead the follow-up observation should be taken into account.

2015 Vol. 12　(1):　121-123 [Abstract]（ 549 ） HTML (1 KB)  PDF  (971 KB)  ( 224 )

Objective：To analyze the clinical effect of biofeedback electrical stimulation， and family rehabilitation pelvic muscle exercises in the treatment of pelvic floor dysfunction diseases. Method：120 cases of maternal， prenatal screening and diagnosis for pelvic floor dysfunction were selected from July 2013 to March 2014 in our hospital.They were randomly divided into the treatment group and the control group，60 cases in each group.The treatment group was given biofeedback electrical stimulation and family rehabilitation therapy， the control group was only received pelvic floor muscle training， 3 months after treatment， two groups were observed in patients with muscle strength and pelvic floor dysfunction symptoms.Result： After rehabilitation， the pelvic floor muscle strength have different degrees of recovery， the effective rate of the treatment group was significantly higher than the control group， the difference was statistically significant (P<0.05）.Conclusion： Pelvic floor muscle training can improve the myodynamia of pelvic floor strength， so as to achieve the treatment of pelvic floor dysfunction， biofeedback electrical stimulation and rehabilitation treatment of pelvic floor with family muscle training therapy effect is better.

2015 Vol. 12　(1):　127-130 [Abstract]（ 560 ） HTML (1 KB)  PDF  (1022 KB)  ( 831 )

Objective：To explore the effect of the carboxymethyl chitosan oral composite membrane films on pericoronitis of the wisdom tooth disease causing germs.Method：From January 2011 to December 2013，120 cases of wisdom intellectual pericoronitis in our hospital were randomly divided into the observation group and the control group，the observation group were given carboxymethyl chitosan oral composite membrane treatment，the control group were given Ornidazole Iodine Glycerol gelatin sponge treatment，the clinical effect of the two groups were compared.Result：The clinical symptoms of the two group were effectively alleviated，the cure rate of the observation group was 78.3%， the total effective rate was 98.3%， which was significantly higher than 60.0%，91.7% of the control group，the difference was statistically significant（P<0.05）.Conclusion：The effect of carboxymethyl chitosan composite membrane film agent oral pathogens to wisdom tooth pericoronitis obviously，could promote the improvement of clinical symptoms and accelerate the prognosis of patients， it was worth to popularize in clinic.

2015 Vol. 12　(1):　134-136 [Abstract]（ 578 ） HTML (1 KB)  PDF  (1001 KB)  ( 357 )

Objective： To discuss the effectiveness， safety on hemabate（ romethamine） for prevention of postpartum hemorrhage of scar uterine vaginal delivery. Method： 90 scar uterus vaginal delivery patients were chosen in our hospital from 2010 July to 2013 July， and randomly divided into experimental group（ 42 cases） and control group（ 48 cases）. In the experimental group， after delivery of fetusconventional they were given intramuscular injection of oxytocin and hemabate intramuscular injection， the control group at the same time was given motherwort needle intramuscular injection. Two hours and 24 hours postpartum hemorrhage， the incidence of postpartum hemorrhage， the incidence of adverse drug reactions of two groups were compared. Result： The experimental group and control group of 2 hours postpartum hemorrhage 24 hours postpartum hemorrhage， the incidence of postpartum hemorrhage the experimental group were all less than those of the control group， there were significant differences between the two groups（ P<0.05）. The incidence of adverse reaction in the experimental group and the control group was 4.8% and 2.1%， there was no significant difference between the two groups.Conclusion： Hemabate for prevention of postpartum hemorrhage of scar uterine vaginal delivery is more obvious curative effect and less side reaction than motherwort needle.

2015 Vol. 12　(1):　139-141 [Abstract]（ 549 ） HTML (1 KB)  PDF  (1001 KB)  ( 399 )

Objective：To investigate the clinical outcome of posterior Trans-articular V shape osteotomy way for kyphosis secondary to thoracolumbar fracture in elderly. Method：18 elderly patients with thoracolumbar kyphosis caused by delayed osteoporotie vertebral fracture were treated by transpedicular wedge osteotomy or trans-articular V shape osteotomy.Result：Cobb angle was 2.8° in average. and before operation Cobb angle was 12.1° in average.All cases were followed up for 8 months to 26 months（average，14 months）.There was no instrument related complication. The back pain was released in both cases after receiving this treatment. Conclusion：Posterior trans-articular V shape osteotomy way for kyphosis secondary to thoracolumbar fracture in elderly is effective and reliable.

2015 Vol. 12　(1):　144-146 [Abstract]（ 470 ） HTML (1 KB)  PDF  (1722 KB)  ( 330 )

MicroRNAs was seen to play a role in a variety of cancer occurrence and development and a series of biological process as post transcriptional regulation. So far， many studies suggest that the expression of miRNA in various of tumors are different， disorganized miRNAs expressed by acting oncogenes or tumor suppressor genes roles， involved in tumorigenesis， development， invasion and metastasis. In addition， the existence of single nucleotide polymorphism of the miRNAs plays a significant effect in its function， and is closely related to the cancer risk and progress of tumor cells. This article sums up the recent reports， both internal and external， in research on miRNA-149 in human carcinomas.

2015 Vol. 12　(1):　150-153 [Abstract]（ 610 ） HTML (1 KB)  PDF  (1003 KB)  ( 579 )