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中国医学创新

2015 Vol.12,No.11

Published 2016-04-15

ZHANG Jing,HU Ze-cheng,CHEN Zhong-dong.

Objective:To explore curative effect and side effects of the patients with ovarian epithelial cell carcinoma after surgery administered by continous hyperthermic peritoneal perfusion chemotherapy( CHPPC) with lobaplatin in combination with intravenous chemotherapy(IC).Method:46 cases of advanced ovarian carcinoma patients after cytoreductive or radical surgery were selected from July 2007 to July 2009,and were divided into cisplatin group and the Lobaplatin group,23 cases in each group,all of them were treated IC+CHPPC, curative effect and side effects were observed.Result:The 46 patients of two groups finished all six cycles chemotherapy.In Lobaplatin group three-year and five-year survival rates respectively was 69.5%,52.1%,the differences were not statistically significant(P>0.05).Although we find the two groups had statistically significant in some aspects(P<0.05), all the patients could stand them.Conclusion:Continous hyperthermic peritoneal perfusion chemotherapy with Lobaplatin in combination with intravenous chemotherapy are safe and feasible treatment modality for patients with advanced ovary carcinoma.Patients in lobaplatin group have better compliance than cisplatin, but the two medicines both have acceptable complications rates,all have marked improvements in survival.

2015 Vol. 12 (11): 1-4 [Abstract]( 744 HTML (1 KB)  PDF  (697 KB)  ( 415 )

ZHU Wen-biao,ZHENG Shao-qiu,LU Shan-ming,et al.

Objective:To compare the consistency of HER-2 in breast infiltrating ductal carcinoma by IHC and FISH detection.Method:HER-2 of 118 cases with breast invasive ductal carcinoma were tested by FISH and IHC detection,and compared the results correlation.Result:118 specimens of invasive ductal carcinoma were seleced, The results tested by IHC were as follows:14 cases(-);20 cases(1+),55 cases(2+),29 cases( 3+).The results tested by FISH were as follows: 53 cases >2.2, 64 cases <1.8,1 case was 1.8-2.2.HER-2 positive coincidence rate was 96.6%(28/29) by IHC detection in positive cases by FISH detection,HER-2 negative by FISH were in negative of IHC detection, the coincidence rate was 100%(34/34).25 HER-2 positive cases by FISH detection were among 55 cases of HER-2(2+) by IHC detection, and 30 were the negative.5 cases on chromosome multi-body in 17 were found by FISH
detection,its incidence rate was 4.24%.HER-2 expression in 8 cases with of breast cancer exists heterogeneity by IHC detection,and the heterogeneity was also confirmed in FISH detected.Conclusion:HER-2 of breast infiltrating ductal carcinoma by IHC detection was high consistency with FISH detection,HER-2 cases(2+) by immunohistochemical need to be detected by FISH.

2015 Vol. 12 (11): 5-7 [Abstract]( 719 HTML (1 KB)  PDF  (672 KB)  ( 455 )

HOU Yi-bin,LIU Qi,DUAN Guang-feng,et al.

Objective:To analyze and study on effect of radiotherapy in patients with hepatocellular carcinoma using situation and the role of diffusion weighted imaging evaluation.Method:Randomly selected from July 2012 to July 2014, conducted in our hospital oncology radiotherapy of 67 cases of liver cancer patients.Respectively by traditional morphological imaging and diffusion weighted imaging method to evaluate the clinical curative effect of patients, and the
evaluation function of the two methods of comparison, statistics and analysis.Result:The clinical analysis showed that patients with traditional morphological imaging scan no difference between the value of tumor size, before and after was not statistically significant( P>0.05).And diffusion weighted imaging scans of ADC values had significant changes before and after treatment, compared before and after there were significant difference, statistically significant( P<0.05).Conclusion:The use of diffusion weighted imaging in patients with liver cancer radiotherapy curative effect evaluation,can timely, accurately reflect the changes of lesions ADC, therefore, it is a scientific, effective and ideal method to evaluate liver cancer radiotherapy.

2015 Vol. 12 (11): 8-11 [Abstract]( 494 HTML (1 KB)  PDF  (728 KB)  ( 285 )

CHEN Fang.

Objective:To study the value of ultrasonic elasticity imaging techniques in assessment of the artery wall elasticity of patients with type 2 diabetes(T2DM).Method:The carotid, brachial artery elastic function parameters of 40 patients with T2DM were detected by ultrasound elasticity imaging technique.At the same time, 40 cases of outpatient health physical examination were selected as control group.The carotid, brachial artery elastic function parameters of two groups were compared, and analyzed the correlation of the blood sugar, thickness of IMT and carotid, brachial artery B/A. Result:The carotid artery B/A and brachial artery B/A1 in patients with T2DM group were significantly higher than that of control group(P<0.05).The carotid B/A had a positive correlation with thickness of IMT(r=0.574,P<0.05), the thickness of the carotid IMT had a positively correlation with blood sugar levels( r=0.612,P<0.05),and the brachial artery B/A1 had a positive correlation with blood glucose levels(r=0.548,P<0.05).Conclusion:The ultrasound elasticity imaging techniques can rapid and effective evaluation early changes in the artery wall elasticity of patients with
T2DM.

2015 Vol. 12 (11): 11-13 [Abstract]( 656 HTML (1 KB)  PDF  (672 KB)  ( 297 )

LUO Yi-zhi,TAN Xiao-hui,WU Wei-ming,et al.

Objective:To observe the concentration and clinical meaning of plasma homocysteine on chronic heart failure patients(CHF).Method:There were 200 patients, 100 of them do not have CHF( control group),100 of them have CHF(CHF group).The CHF patients were separated as group Ⅱ,group Ⅲ,group Ⅳ according to the America New York Heart Association( NYHA).The plasma homocysteine,N-terminal B-type natriuretic peptide( NTproBNP)
and left ventrical eject function(LVEF) were compared on all of the patients.Result:The plasma homocysteine was higher on the group CHF than on the control group(P<0.05).The plasma homocysteine was different from group Ⅱ to group Ⅲ and group Ⅳ(P<0.05).The NT-proBNP was higher on the group CHF than on the control group(P<0.05).The plasma NT-proBNP was different from group Ⅱ to group Ⅲ and group Ⅳ(P<0.05).The LVEF was lower on the
group CHF than on the control group(P<0.05).The LVEF was different from group Ⅱ to group Ⅲ and group Ⅳ(P<0.05).The plasma homocysteine was positively correlated with NT-proBNP, and negatively correlated with LVEF on the CHF patients.Conclusion:The plasma homocysteine is higher on the CHF, it may be considered as one of the important CHF markers.

2015 Vol. 12 (11): 14-16 [Abstract]( 499 HTML (1 KB)  PDF  (676 KB)  ( 186 )

CHEN Kai,GU Shu-yong,YANG Yi-feng.

Objective:To study the value of laparoscopic surgery in acute appendicitis.Method:From September 2012 to September 2014, the clinical data of 128 cases of acute appendicitis were admitted, according to figures randomized law principles, the patients were divided into two groups, 64 cases in each group.The control group with open surgery, laparoscopic surgery observation group, two groups were compared blood loss, operative time, exhaust
recovery time, postoperative ambulation time, postoperative antibiotic use time, length of stay and complication rates occur.Result:(1)Intraoperative blood loss, operating time and exhaust recovery time in the observation group were shorter than the control group, compared with statistical significance(P<0.05).(2)Postoperative bed activity time in the observation group, postoperative antibiotic use time and hospital stay were lower than the control group, compared with statistical significance( P<0.05).(3)The main complications in patients with incision infection, intestinal obstruction,
abdominal abscess.of complications in 4 patients in observation group, the incidence of complications was 6.25%.Of complications in 8 patients in control group, the incidence of complications was 12.50%.Observation group complication rate is lower than the control group,there was biggish difference compared with statistical significance(P<0.05).Conclusion:Laparoscopic surgery in the treatment of acute appendicitis disease has a higher application value and is
beneficial to reduce the intraoperative blood loss,let patients bed as soon as possible,shorten the hospitalization time and antibiotic use time,reduce the incidence of complications,worthy of clinical popularization and application.

2015 Vol. 12 (11): 16-19 [Abstract]( 612 HTML (1 KB)  PDF  (691 KB)  ( 285 )

LI Ke-rong,CHENG Shi-li,ZOU Jin-yi.

Objective:To analyze the effect on the related factors of renal osteopathy of different blood purification method.Method:From January 2009 to August 2014,a total of 326 patients with renal osteopathy treated in our hospital by blood dialysis were randomly divided into two groups.163 cases of patients in the control group were treated using common blood purification method; 163 cases of patients in the observation group were treated with combinedtype blood purification methods.The blood blood calcium, phosphorus, parathyroid hormone,the change of the beta 2-microglobulin and the calcium-phosphorus product in the two groups before and after treatment were compared.Result:After treatment, blood calcium content of the patients in the observation group significantly increased(P<0.05),and the blood phosphorus,parathyroid hormone,beta 2-microglobulin and calcium-phosphorus product significantly decreased(P<0.05).But all the indexes of patients of the control group changed non-significantly.Clinical therapeutic effect of the observation group was significantly higher than the control group, but the adverse reaction was significantly lower than that in the control group(P<0.05).Conclusion:The effects on the related factors of renal osteopathy of different blood purification methods are different.Combined-type blood purification methods can better remove patients parathyroid hormone and beta 2-macroglobulin,and repair the body calcium phosphorus metabolism disorder phenomenon.

2015 Vol. 12 (11): 20-23 [Abstract]( 495 HTML (1 KB)  PDF  (694 KB)  ( 226 )

LIU Jun,DONG Xu-dong.

Objective:To study the expression of helicobacter pylori in indigestion pregnant women,investigate the relationship between helicobacter pylori infection and indigestion.Method:From March 2012 to September 2013 alone, 90 cases of indigestion pregnancy pregnant women were selected as the research object, the selection over the same period 90 cases with no history of digestive symptoms and gastrointestinal disease pregnant women as control group.Hp and CagA in two groups was analyzed.Result:The positive serum of H.pylori was slightly higher than the control group in the indigestion group but there was no significant difference( 68% vs59 %,P>0.05).In H.pylori positive cases with gastrointestinal symptoms and no digestive tract symptoms in the two groups of CagA positive rate had significant difference(vs43%62%,P=0.0002).Conclusion:In the pregnant women of indigestion,increased Hp infection is not statistically
difference, however, the incidence of indigestion in cagA positive serum was significantly higher than that of cagA negatie,thus, highly pathogenic Hp strains is closely related to the pregnant women indigestion.Clinical treatment,Hp strains should be clear as a breakthrough point,through clearing Hp strains, relieve the symptoms of indigestion.

2015 Vol. 12 (11): 23-25 [Abstract]( 586 HTML (1 KB)  PDF  (671 KB)  ( 301 )

GAO Hua.

Objective: To summarize the barbiturate coma therapy in clinical curative effect and prognosis of severe head trauma. Method: 82 patients of severe craniocerebral trauma were selected in our hospital from February 2013 to August 2014 during the period of accepted the diagnosis and treatment,and randomly divided into two groups,41 cases in each group.The control group were underwent routine therapy, while the experimental group was treated barbiturate coma therapy, at the same time,two groups’ treatment and prognosis were contrasted and analyzed.Result: Two groups 24 hours and 48 hours after treatment gived the real-time monitoring, the test results showed that the two groups in the cavity of cerebrospinal fluid pressure and cerebral blood flow and other clinical indicators were dropped. Compared with control group, the experimental group patients clinical index fell more, the difference was statistically significant(P<0.05).Conclusion:The clinical barbiturate coma therapy on the clinical curative effect and prognosis of severe head trauma effect is significant, in addition to being able to control the cerebrospinal fluid pressure in patients with cranial cavity, maximize the cerebral perfusion, at the same time also can improve the patients’ symptoms of cerebral ischemia or hypoxia,plays a comprehensive protection for the brain, thus it has the high feasibility and is worth promoting.

2015 Vol. 12 (11): 26-29 [Abstract]( 632 HTML (1 KB)  PDF  (703 KB)  ( 457 )

ZHONG Jia-jing,DONG Hua.

Objective:To investigate the application and clinical experience with follicular phase mild ovarian stimulation joint luteal phase ovarian stimulation applied for in patients with poor ovarian response(P0R) in the cycle of in vitro fertilization and embryo transfer( IVF-ET).Method:Totally 68 patients with POR were applied IVF cycles,They all accepted follicular phase mild ovarian stimulation and the subsequent luteal phase ovarian stimulation,The clinical
data including average number of retrieved oocytes and proportion of retrieved oocytes,fertilization rate and number of frozen embryos, rate of embryo high quality and pregnancy rate in labor were analyzed.Result:The fertilization rate and rate of embryo high quality of two phases not statistical difference(P>0.05),but the average number of retrieved oocytes,proportion of retrieved oocytes,number of frozen embryos and pregnancy rate of luteal phase ovarian stimulation were significantly higher than follicular phase(P<0.05),and the average number of retrieved oocytes,proportion of retrieved oocytes,number of frozen embryos of follicular phase mild ovarian stimulation joint luteal phase ovarian stimulation significantly more than simply follicular phase(P<0.05),and 14 patients were pregnancied ultimately.Conclusion:In patients with POR receive luteal phase ovarian stimulation made the average number of retrieved oocytes, number of frozen embryos and pregnancy rate higher,and follicular phase mild ovarian stimulation joint luteal phase ovarian stimulation
applied for in patients with( P0R) can effectively improve the clinical pregnancy outcome.

2015 Vol. 12 (11): 29-31 [Abstract]( 601 HTML (1 KB)  PDF  (673 KB)  ( 347 )

LI Zheng-xue.

Objective:To investigate the affect of the serum B lymphocytes stimulating factor(BlyS) on the anti-IgE antibody and anti-FcεRI antibody of the patients with chronic idiopathic urticaria. Method: 100 cases of patients with chronic idiopathic urticaria were selected as disease group, 100 cases of healthy people in the same period were selected as the healthy group. The serum level of the BlyS, anti-IgE antibody and anti-FcεRI antibodies were detected;the B lymphocytes from the peripheral blood of the disease group patients were isolated and cultured, and divided into two shares, add BlyS in one share as the experimental group,another share as blank control group,the level of the anti-IgE antibody and anti-FcεRI antibodies were detected. The relationship among the BlyS,anti-IgE antibody and anti-FcεRI antibodies were analyzed. Result:The serum levels of the BlyS,anti-IgE antibody and anti-FcεRI antibodies of the disease group were significantly higher than the healthy group,the differences had statistical significance( P<0.05).The levels of the BlyS,anti-IgE antibody and anti-FcεRI antibody of the experimental group were significantly higher than the control group, the differences had statistical significance(P<0.05). The levels of the anti-IgE antibody and anti-FcεRI antibodies of the experimental group were positively correlated with the BlyS( r=0.765,0.722,P<0.05).Conclusion:BlyS can stimulate B lymphocytes to produce the anti-IgE antibody and anti-FcεRI antibodies of patients with chronic idiopathic urticaria, this may be related to the pathogenesis of chronic idiopathic urticaria.

2015 Vol. 12 (11): 32-34 [Abstract]( 435 HTML (1 KB)  PDF  (694 KB)  ( 319 )

XIONG Lin, XIA Bing-shu, WANG Jun,et al.

Objective:To compare the clinical effect in patients who underwent operation for intrertochanteric femoral fractures using dynamic hip screw(DHS) versus proximal femoral nail antirotation(PFNA).Method:A retrospective study of 223 patients with intertrochanteric fractures who received a DHS or a PFNA from Jan 2002 to Jan 2013 were undertook.There were 121 patients in DHS group, whereas 102 patients in PFNA group.The age, sex distribution, duration of operation, blood loss, bedridden time, duration of hospitalization, rate of complications, time to union, harris hip joint functional score were recorded and assessed.Result:The patients got followed up for 12 to 20 months.No difference was found between two groups in age,sex distributions and type of fracture.Statistically significant differences were found in operation time,fracture union time,rate of complications,and harris hip joint functional score
between the two groups(P<0.05).There were no significant difference in bedridden time,duration of hospitalization and total blood loss.Conclusion:DHS and PFNA can treat intertrochanteric fractures with good result.PFNA is superior to DHS in less invasive, reducing complication rates,recovering hip joint function;it is an ideal fixation method for treating all type of intertrochanteric fracture especially for unstable femoral intertrochanteric fracture and patients with severe osteoporotic.

2015 Vol. 12 (11): 35-39 [Abstract]( 547 HTML (1 KB)  PDF  (818 KB)  ( 379 )

LIANG Cui-miao,PAN Min-yi,HUANG Ren,et al.

Objective:To investigate and analyze the clinical effect of budesonide combined with montelukast in treatment of children with cough variant asthma.Method:60 cases of infantile cough variant asthma from April 1,2013 to April 30, 2014 in our hospital were selected,according to the treatment methods they were divided into test group( 30 cases) and control group( 30 cases).Control group patients were given budesonide treatment,experimental group patients were given oral montelukast on the basis of the control group,their therapeutic effect were observed.Result:The treatment efficiency of test group( 96.67%)was higher than that in the control group( 73.33%),the test group the recurrence rate(6.67%) was lower than that of the control group(20.00%),after treatment,relieve cough time,cough disappeared time of the test group were significantly better than the control group(P<0.05).Conclusion:Budesonide
combined with oral montelukast has good clinical effect on treating children with cough variant asthma,they improve the treatment efficiency and the patients’ PEF,FEV1,FVC,FEV1/FVC and a number of items of pulmonary function,clinical can consider expanding application.

2015 Vol. 12 (11): 39-41 [Abstract]( 545 HTML (1 KB)  PDF  (683 KB)  ( 230 )

LIU Wang,WU Ge-yi,LUO Guo-quan,et al.

Objective:To observe impact of Chuankezhe injection combined with thymic peptide on IgE、IL-4 in patients with bronchial asthma.Method:86 patients with diagnosis of bronchial asthma were randomly divided into treatment group and the blank control group, 2 weeks after treatment, patients with venous blood was drawn to observe blood IgE,IL-4 change, the differences between the two groups were compared.Result:The treatment group for Chuankezhe injection combined with thymic peptide treatment IgE,IL-4 improved than control group,the difference was statistically significant(P<0.05).Conclusion:Chuankezhe injection in combination with thymic peptide treatment has good therapeutic effect in patients with bronchial asthma,can improve the IgE,IL-4 and achieves very good smooth wheezing and immunomodulatory effect,worth clinical recommendations.

2015 Vol. 12 (11): 42-44 [Abstract]( 565 HTML (1 KB)  PDF  (674 KB)  ( 362 )

LIANG Guo-quan,ZHAI Yong-xin,CHEN Yi-ming.

Objective: To analyze the clinical application effects of Ventricular premature beat treated by radiofrequency ablation. Method: 60 patients who suffered from the ventricular premature beat and who accepted treatment in our hospital from April 2012 to April 2013 were selected as the research objects,and were randomly divided into the control group and the observation group, 30 patients in each group. In the control group, the patients suffered from the ventricular premature beat were treated with the propafenone, while in the observation group, the patients suffered from the ventricular premature beat were treated with radiofrequency ablation. Then, the treatment effects of these two groups were analyzed and compared. Result: In the control group, the significant effective rate of these patients was 56.7% and the total effective rate was 73.3%. However, in the observation group, the significant effective of these patients was 93.3%  and the total effective rate was 100%. Thus, the differences were evident and there were statistical significance(P<0.05).In addition, in the observation group, the recurrence rate of these patients after the treatment was 6.7%, which was evidently lower than 33.3% in the control group,the difference was statistically significant(P<0.05). Furthermore, after treatment,3 patients in the control group suffered from the adverse drug reaction and the related serious complications.However, in the observation group no patients suffered from the adverse drug reaction and the related serious complications.In addition, according to the 24-hour dynamic electrocardiogram, the time of bigeminy coupled rhythm and the trigeminal beats in the observation group was 0 and the total number of early room were( 168±86), which was evidently lower that that in the control group , the differences were statistically significant(P<0.01).Conclusion:The clinical application effects of ventricular premature beat treated by radiofrequency ablation is good and has high success rate and low recurrence rate. In addition, the complications are few. Thus, it should be promoted in the clinic applications.

2015 Vol. 12 (11): 44-46 [Abstract]( 543 HTML (1 KB)  PDF  (672 KB)  ( 464 )

HUANG Bin, HUANG Yong-yi, LIU Fei, et al.

Objective: To discuss the effect of Anatomic locking plate and Non locking plate in treatment of calcaneous fracture. Method: 80 patients with calcaneous fracture in our hospital from 2011 July to 2013 June were randomly divided into control group( 40 cases) and observation group( 40 cases). The control group was non locking plate, the observation group was anatomical locking plate, compared the curative effect of two groups. Result: The total effective rate of the observation group was higher than that of the control group, the amount of intraoperative bleeding was less than that of the control group,operation time and the fracture healing time were shorter than those of the control group,the incidence rate of complications was lower than that of control group. There was statistical significance( P<0.05).Conclusion: In the calcaneus comminuted fracture patients, anatomic locking plate internal fixation treatment scheme,the better curative effect, patients less blood loss, fracture healing time and postoperative short operation time, low incidence of complications, worthy of clinical application.

2015 Vol. 12 (11): 47-49 [Abstract]( 525 HTML (1 KB)  PDF  (673 KB)  ( 295 )

ZHANG Yong-xiang.

Objective:To evaluate the long-term effect of atovastatin calcium on carotid atherosclerosis plaque in patients with acute cerebral infarction.Method:100 cases of patients in our hospital were chosen as the experimental objects.,and were divided into experimental group and control group,control group were treated with routine  treatment,and the experimental group were treated with atovastatin calcium on the basis of control group,the TC,TG,LDL,HDL,hs-CRP,IMT,plaque area and adverse reaction between two group were compared.Result:After 12 months’treatment,TC,TG,LDL,HDL,hs-CRP of the experimental group were statistically better than that of the control group(P<0.05).The plaque area and IMT of the experimental group were statistically lower than that of the control group(P<0.05).The adverse reaction between two group had no significant difference( 字2=1.375,P<0.05).Conclusion:Atovastatin calcium could improve the blood lipid level,reduce the inflammation response,has a stable and promote the ablation effect on plaque.

2015 Vol. 12 (11): 49-51 [Abstract]( 572 HTML (1 KB)  PDF  (683 KB)  ( 325 )

YANG Hui-min.

Objective:To explore the clinical curative effect of the vagina operation in treatment of unruptured tubal pregnancy.Method:According to the actual operation method in patients with 86 cases of fallopian tube pregnancy in our hospital admitted patients were divided into experimental group 42 cases and control group with 44 cases.The patients in the exeperimental group received transvaginal tubal resection,patients incontrol group were treated with laparoscopic tubal resection,after operation,morbidity,complications and hospitalization expenses were compared. Result:Operation time,bleeding volume,possoperative exhaust time and hospital stay of two groups were no significant difference(P>0.05),while the postoperative morbidity,incidence of complications and hospitalization costs in the experimental group were lower than the control group,with significant ficant difference( P<0.05).The experiment group for one years the pregnancy rate was 71.43%, one yeas again ectopic pregnancy rate was 19.04%,compared with the control group no significant difference conclusion.Conclusion:Transvaginal operation in treatment of tubal pregnancy by laparoscopic operation compared with similar efficacy,but with a low cost of hospitalization,abdominal wound,low rate of postoperative analgesia, no electrical injury,fast recovery,high degree of satisfaction,is obviously better than that of laparoscopic operation,the higher the value of clinical application.

2015 Vol. 12 (11): 52-55 [Abstract]( 682 HTML (1 KB)  PDF  (705 KB)  ( 505 )

ZHOU Jian,WANG Ping-hua,CHANG Bing,et al.

Objective:To analyze the Desogestrel and Ethinylestradiol Tablets( Marvelon) effect in the treatment of uterine scar incomplete drug abortion intrauterine residue.Method:142 cases of medicine logistics postpartum were selected in our hospital from May 2013 to May 2014, in which two weeks patients were with persistent vaginal bleeding,were randomly divided into two groups, the observation group of 72 cases with Desogestrel and Ethinylestradiol Tablets
combined with motherwort conservative treatment, the control group of 70 cases with drug abortion decidual residue operation curettage therapy, compared two the therapeutic effect of the group. Result: The observation group hemostasis rate was 84.7%(61/72) was significantly higher than that in control group 47.1%(33/70), with significant difference(P<0.05);the observation group after treatment of uterine volume( 143.6±50.2)cm3 was significantly lower than that of control group( 169.9±54.4)cm3,endometrial thickness( 0.8±0.2)cm also significantly less than that of the control group( 1.4±0.3)cm,the duration of vaginal bleeding after drug( 5.6±2.2)d was significantly shorter than that in control group( 9.4±2.5)d,gestational residue discharge time( 4.2±2.5)d was significantly shorter than that in control group( 6.8 ±2.8)d,menstruation was significantly better than the control group, the difference differences were statistically significant(P<0.05).Conclusion:Marvelon in the treatment of incomplete abortion Intrauterine Residue after the hemostasis rate is high, the vaginal bleeding time is short,and which can regulate menstruation and promote uterine recovery.

2015 Vol. 12 (11): 55-58 [Abstract]( 590 HTML (1 KB)  PDF  (693 KB)  ( 274 )

LIU Fang,ZHONG Ri-ying,TU Yan-qing,et al.

Objective:To study the clinical efficacy of montelukast in children with allergic purpura of plasma cytokine levels .Method: 100 children with allergic purpura were selected in our hospital as research subjects,and were randomly divided into two groups, the control group of children were given anti-histamine drugs, anti-infective drugs and calcium, vitamin C and other conventional drugs.The observation group was treated with montelukast chewable tablets treatment on the basis of conventional therapy. In two weeks for a course of treatment,the clinical effect of plasma cytokine levels in patients before and after treatment were compared and observed.Result: IL-6,IL-8 and TNF-α expression levels observed before the treatment,two groups of patients showed no significant difference(P>0.05);after treatment, the expression levels of three indicators had decreased significantly,and compared with before the treatment, the differences were statistically significant(P<0.05); observation group’ indicators decreased more than control group, the difference was statistically significant(P<0.05).Observation group and control group of patients with clinical response rates were respectively 96.0% and 78.0%, the difference was statistically significant(P<0.05).Conclusion:Montelukast treatment of children with allergic purpura have clinical efficacy, safety,and good benefits,
cytokines can be adjusted within the plasma of children, promote the improvement of immune function in children, worthy of clinical application.

2015 Vol. 12 (11): 58-60 [Abstract]( 604 HTML (1 KB)  PDF  (683 KB)  ( 203 )

ZHANG Kai-fu, MOU Ming-yan.

Objective:To compare the clinical value of spiral CT with high-frequency ultrasound in the diagnosis of atypical acute appendicitisl.Method:To retrospectively analyze the medical records of 50 patients with clinical diagnosis of atypical acute appendicitisl.Before surgery, patients were given spiral CT and high frequency ultrasound examination to surgery-pathology results as the gold standard, the results of the spiral CT and high-frequency ultrasonography were compared and analyzed.Result:Pathological diagnosis:normal appendix 17 cases, 33 cases of acute appendicitis( 12 cases of edema, cellulitis for 12 cases, 9 cases of gangrenous).Spiral CT diagnosis of acute appendicitis atypical sensitivity, specificity and accuracy were significantly higher than those of the high-frequency ultrasound between the two groups, which was statistically significantly different( P<0.05).Spiral CT in acute edema and cellulitis appendicitis diagnosis the correct rate was higher than that of the high-frequency ultrasound, the difference was statistically significant( P<0.05); for gangrenous appendicitis, spiral CT were correctly diagnosed with high-frequency ultrasound, the accuracy was 100%, the difference was not statistically significant.Conclusion:In the diagnosis of acute appendicitis in the atypical, the spiral CT high-frequency ultrasound advantage.For suspected acute appendicitis in patients with atypical, such as high-frequency ultrasound examination is negative, should further spiral CT scan to confirm the diagnosis.

2015 Vol. 12 (11): 61-63 [Abstract]( 609 HTML (1 KB)  PDF  (673 KB)  ( 198 )

YANG Le,RAO Hai-jun,DENG Zhi-rong.

Objective:To compare treatment significance of two different methods for complex fractures of distal disease.Method:In our hospital orthopedic surgery were randomly collected 200 cases of distal femoral fractures were complex, the application of minimally invasive stabilization system( LISS) and anatomical plate in the treatment of  complex fractures of the distal femur surgery patients were randomly divided into anatomical plate group sequence and LISS plate group.Operative time, surgical incision, blood loss, complications and healing time, etc., and with the modified HSS score to evaluate the degree of improvement in postoperative knee function were compared.Result:LISS plate group operative time, surgical incisions, complications and healing time were significantly less than the anatomical plate group,and the group HSS score significantly better than anatomical plate group, the difference was statistically significant(P<0.05).Conclusion:LISS and anatomical plate in the treatment of distal femoral fractures can be complicated to obtain satisfactory results, but LISS fixation system with angular stability, fracture fixation reliably reflect the principles of minimally invasive, thus reducing the risk of pain and treatment of patients, reducing the incidence of complications from the overall perspective of the patients did not significantly increase the cost of treatment, and promoting the harmonious development of the doctor-patient relationship, worthy of clinical application.

2015 Vol. 12 (11): 63-65 [Abstract]( 664 HTML (1 KB)  PDF  (673 KB)  ( 364 )

LIANG Hui-ping,WANG Gui-qiu,LI Zhi-zhong,et al.

Objective:To acquaint the status of hepatitis B virus( HBV) infection in nursing students,and provide data for occupational protection of hepatitis B.Method:Hepatitis B serological markers were measured in nursing and midwifery students of 2012 grade from a college of Guangxi before clinical practice,and questionnaire survey of Hepatitis b vaccination situation was proceeded in those five serological markers negative,statistical results were analyzed.Result:The detection results of 638 nursing students display,the positive rate of HBsAg was 5.96% in total,HBeAg positive rate was 1.10%, HBeAb positive rate was 2.98%;five HBV markers negative in 339 cases, accounted for 53.13% of the total number.The results of a questionnaire survey showed that 79.88% of nursing students thought hepatitis B serological markers detection before practice was necessary, but awareness rate for the hepatitis B vaccine prevention was low.Conclusion:20-22 years old nursing students HBsAg positive rate are lower than the HBsAg of our country carrying rate level, large numbers of people are lack of specific immunity for HBV, and the awareness of hepatitis B vaccination rate is low.The propaganda of knowledge of hepatitis B prevention in nursing students should be increased,high-risk individuals should get vaccinations against hepatitis B or reseed vaccine.

2015 Vol. 12 (11): 66-69 [Abstract]( 476 HTML (1 KB)  PDF  (691 KB)  ( 285 )

Du Ya-ting.

Objective:To know the caries status in preschool children in Changping district.Method:The descriptive statistics method was used to analyze the relative data in Changping Annual Report of 0-6 Years Old Group Child Care from 2006 to 2012.Result:3-6 years old preschool children caries rate increased year by year; the rate of caries started to decrease by 2012 with the development of the free oral fluoride foam to prevent dental caries service from 2010 in Beijing; the rate of new caries increased year by year from 2006 to 2009 up to the rate of 40.14%; it started to decrease from 2010.Conclusion:The oral health care for children in nurseries and kindergartens should be strengthened;children’s dental caries preventive work level should be improved;parents’,teachers’ and children’s health education on caries should be done with enough attention;therefore, the children caries rate and new caries rate could be decreased,and the physical and mental health development of preschool children could be improved.

2015 Vol. 12 (11): 69-72 [Abstract]( 582 HTML (1 KB)  PDF  (744 KB)  ( 387 )

ZHANG Yue,SONG Wei-rong,CHEN Li-ping.

Objective:To explore the superiority of modern university medical applied talents training mode.Medical students need to do professional, active, positive, careful, the education of medical ethics, and should be able to meet the needs of modern society.Method:Optional class 2010 grade English class teaching was selected as the research object, 20 class for the control group( the traditional teaching mode), 21 class as the experimental group( the applied
talents training mode).20 classes studied as the traditional method of teachers taught, students’ learned methods.21 class used the teaching method of cultivating applied talents.At the end of the whole course, carries on the theory of the exam, according to a scale to carry on the classification, the results of the experimental group and the control group,were compared and analyzed.Result:Through questionnaire, reflects the medical students’ approval of new methods,new model of teaching and requirements, students could set off from reality to view of modern medicine and society.After a full semester teaching, two groups of final theory test scores were compared, proficiency group than the control group significantly increased, and the sum of outstanding and good experimental group than the control group.Internship phase the results of the experimental group than the control group with obvious prominent, especially on the complete case analysis problem was significantly improved.There was the outstanding analysis, handle problems and practical ability.Conclusion:Medicine itself is a real medicine itself is a practical science, medical education need to fully mobilize students’ subjective initiative, to cultivate the students’ self-confidence and creativity cultivation of noble medical ethics.Applied talents training mode can enhance the students’ subjective actively search ability, flexible comprehensive logical ability, improve the ability of independent analysis, handle problems.

2015 Vol. 12 (11): 73-75 [Abstract]( 436 HTML (1 KB)  PDF  (671 KB)  ( 376 )

GAO Yi-ying, MA Hong, ZHAO Yan-fang, et al.

Clinical practice is an essential part of medical students training process, an important approach to cultivate new era of high-quality talents of medicine. However, in the face of the particularity of the current social transformation, facing the practice teaching of legal environment, cultural environment, social environment, great changes which have taken place in the influence factors in the process of practice is far more than ever before. Therefore,it is necessary to explore various unfavorable factors existing in the practice process, maximize the to ensure the quality of practice teaching, help students to establish clinical thinking, causes the student to apply the correct clinical thinking in clinical practice to accurately collecting medical history, history analysis, observation of condition, comprehensive thinking. Through the system of theoretical study and clinical technical operation training, causes the student to master the disease, reasoning, the ability of disease, diagnosis of diseases.

2015 Vol. 12 (11): 76-78 [Abstract]( 470 HTML (1 KB)  PDF  (690 KB)  ( 243 )

YANG Yan.

Objective: To investigate patients with the non-invasive ventilation during treatment assessment and care measures.Method: 50 patients were treated in nursing assessment and based on the assessment results,the appropriate care measures. Result:In 50 patients, 45 cases of treatment were effective, 5 cases of ineffective.Conclusion: The use of non-invasive ventilator patients assessment and care,enabling patients to actively cooperate to improve patients’ compliance,increase patients’ comfort,reduce the incidence of complications, and achieve satisfactory results.

2015 Vol. 12 (11): 79-80 [Abstract]( 579 HTML (1 KB)  PDF  (652 KB)  ( 204 )

QI De-mei.

Objective:To explore the effect of psychological pressure on nursing intervention for young patients with rectal cancer postoperative fistula.Method:Rectal cancer after colostomy patients below the age of 40 were randomly divided into control group and observation group.Control group being routine health education,while observation group being the nursing interventio on the basis of the routine health education.Result:The pressure of observation group was
smaller than that of observation group(P<0.01).Conclusion:Systematic nursing intervention on young colostomy patients with postoperative rectal cancer can realease the psychological pressure,improve the understanding about the disease,make the patient actively cooperate with treatment and care.So the nursing effect is superior to the traditional nursing method.

2015 Vol. 12 (11): 81-83 [Abstract]( 615 HTML (1 KB)  PDF  (669 KB)  ( 233 )

CHEN Shao-fen, LIANG Feng-zhen, LI Xue-fen,et al.

Objective:To study the effect of psychological nursing intervention on depression.Method:64 cases of depression were selected in our hospital from July 2011 to April 2013, 32 cases were randomly divided into two groups,using conventional nursing, and antidepressant treatment for the control group, on the basis of antidepressant treatment given psychological nursing intervention for the observation group.Result:Control group using conventional care patients’
compliance was 56.25%, while the use of psychological nursing intervention group patients compliance was 87.50%, the difference between the two groups(P<0.05).Compared with two groups at the end of the period of treatment was found that in the control group were treated, the total effective rate was 75.00% group total effective rate of treatment was as high as 96.88%, a significant difference was found in two groups(P<0.05).Conclusion:Psychological nursing intervention has important effect on treatment of depression patients, can improve the patients compliance,improve the treatment effect,worth clinical promotion and application.

2015 Vol. 12 (11): 84-86 [Abstract]( 671 HTML (1 KB)  PDF  (684 KB)  ( 364 )

SHI Yu-xia,ZHANG Li-min,CHANG Yan-yan,et al.

Objective:To study and analyze the clinical nursing result of 42 cases of children with acute bronchiolitis.Method:In our hospital from March 2013 to April 2014 in the treatment of acute bronchiolitis in children with 42 cases as the research object, and divided into two groups according to the clinical nursing method( observation group, control group), 21 cases in each group,the control group were given conventional nursing, the observation group with control group based on the routine nursing care in children with the given comprehensive clinical nursing, observe the clinical results of two groups of children.Result:The clinical results showed that the observation group patients in clinical treatment of total efficiency was better than that of the control group patients, the clinical differences between the two groups was obvious(P<0.05),with statistical significance;the observation group clinical nursing satisfaction than the
control group, two groups of clinical differences more obvious(P<0.05),with statistical significance.Conclusion:The clinical nursing of acute bronchiolitis in children, to give the comprehensive nursing, such as:keeping respiratory tract unobstructed, give oxygen, psychological nursing, can improve the cure rate and nursing satisfaction, clinical effect is remarkable, worthy of popularization.

2015 Vol. 12 (11): 86-88 [Abstract]( 504 HTML (1 KB)  PDF  (686 KB)  ( 222 )

JIANG Ying-luan.

Objective:To observe and compare with the clinical efficacy of Ziwuliuzhu method or acupuncture and moxibustion method treatment of insomnia. Method:124 outpatients with insomnia were randomly divided into two groups,62 cases in the treatment group,62 cases in the control group, the treatment group in accordance with the law of midnight-noon timing by selecting acupoints,this was used by the method of tonifying mother and purging son,according
to the twelve Earthly Branches in time,at the same time with the twelve meridians of breath and blood running sequential acupuncture therapy. The control group according to the routine acupuncture acupoint such as Baihui, Neiguan,Shenmen etc,with acupuncture treatment at any time, the treatment effect between the two groups was compared.Result:The total efficiency of the treatment group was 93.8% and 85.5% in the control group, there was a significant
difference in the two groups( P<0.05).The PSQI and sleep rate of the two groups had a significant differences(P<0.05).Conclusion:According to the method of Ziwuliuzhu acupoints,the timing of acupuncture and moxibustion has a significant efficacy in treating insomnia. It is worthy of popularization and application.

2015 Vol. 12 (11): 89-92 [Abstract]( 606 HTML (1 KB)  PDF  (692 KB)  ( 1352 )

HU De-ming.

Objective:To explore the clinical effect of acupotomy with ozone in the treatment of refractory rotator cuff pain.Method:100 cases of patients with refractory rotator cuff pain in our hospital,were randomly divided into the control and observation group with 50 cases of each group.The ontrol group used local injection, the observation group used acupotomy with ozone.The range of shoulder joint motion, shoulder joint pain level and efficacy of two groups were
compared.Result:The range of shoulder joint motion in both groups was increased, and the observation group increased more significantly, the differences were statistically significant(P<0.05).The VAS score in both groups was decreased,and the observation group decreased more significantly, the differences were statistically significant(P<0.05).The observation group treatment excellent and good rate was 96.0% higher than the control group 72.0%( P<0.05). Conclusion:Acupotomy with ozone is better than local injection in the treatment of refractory rotator cuff pain.It is safe and simple, little trauma, worthy of promotion and application.

2015 Vol. 12 (11): 92-94 [Abstract]( 512 HTML (1 KB)  PDF  (671 KB)  ( 213 )

ZHAO Wen-long,LIAO Qing-ping,LIU Jing-jie.

Objective:To explore the setup errors of two different position fixing in radiotherapy of esophagus
cancer.Method:50 cases of esophagus cancer patients with radiotherapy were randomly divided into two groups,group A
25 cases use a simple vacuum pad fixing technology,25 cases of group B use Head-neck-shoulder omentum droping
Combined with the foot "U" fixed method,The setup accuracy of marked method of two groups were compared.
Result:The differences on Three-dimensional setup errors were significantly(t=3.78,P<0.05).Conclusion:The
positioning accuracy of Head-neck-shoulder omentum droping combined with the foot "U" fixed method in treatment of
esophagus cancer is significantly improved and recommended for clinical use.

2015 Vol. 12 (11): 95-97 [Abstract]( 530 HTML (1 KB)  PDF  (671 KB)  ( 221 )

LI Chun-yan,MA Xiao-liang,ZHAO Ning,et al.

Objective: To explore the rational emotive therapy effect in the prevention of occupation burnout of medical staff. Method: From July 2013 to October 2014, voluntary participation in the activities of the medical staff were randomly selected,including 500 clinical frontline nurses and 300 doctors as the research object, the reasonable mood therapy for 2 months on the existence of occupation burnout 100 nurses and 60 patients with the doctor were carried on, a questionnaire survey was conducted before and after the intervention of occupation burnout occupation burnout,score statistics before and after intervention. Result: After the intervention , nursing staff and medical personnel occupation burnout scores were respectively( 167.38±8.43),(162.83±11.29),compared with( 217.83±15.29)and( 209.43±14.27) before the intervention were significantly decreased, the differences were statistically significant
(t=14.283,11.853,P<0.05). Nursing staff and medical personnel after the intervention,the proportion of severe scores decreased significantly, the proportion of mild and moderate scores improved significantly, the differences were statistically significant(P<0.05).Conclusion: The rational emotive therapy can improve the ease of the medical staff occupation burnout.

2015 Vol. 12 (11): 98-100 [Abstract]( 566 HTML (1 KB)  PDF  (681 KB)  ( 302 )

ZHAO Yan-ping, YE Fu-cai,ZHOU Jin-hui,et al.

Objective:To investigate the clinical pathway used in recovery period of general anesthesia to control the complications.Method:43 cases of patients after general anesthesia in our hospital from October 2013 to October 2014 were selected as the control group and the experimental group.The effect of clinical pathway used in anesthesia recovery period to control the complications and the patient satisfaction was analyzed.Result:The incidence of complications in experimental group was significantly lower than that of control rol group( X2=5.119,P<0.05).And the satisfaction in experimental group was significantly higher than that of control group( Z=2.093,P<0.05).Conclusion:Clinical pathway used in anesthesia recovery period can reduce the incidence and the degree of complications such as respiratory,circulatory and nervous systems and pain, and improve the patients’ satisfaction.

2015 Vol. 12 (11): 101-103 [Abstract]( 596 HTML (1 KB)  PDF  (682 KB)  ( 220 )

WANG Guang-qian,JIANG Cai-hong.

Objective:To study the effects of leukocyte depleted blood transfusion on immune function.Method:162 patients blood transfusion were randomly divided into two groups,the observation group(n=81 cases)and the control group(n=81 cases).The control group was treated through the conventional blood transfusion,while the observation group was treated through leukocyte depleted blood transfusion.T cells subsets and immune globulin protein were measured before and after blood transfusion.Result:No significant difference about mean body temperature was observed between the two groups before and after blood transfusion(P>0.05).Before and after transfusion temperature mean difference, the observation group was significantly lower than that of the control group(P<0.05).Transfusion reaction rate in the observation group was significantly lower than the control group(P<0.01).Serum CD4+,CD4+/CD8+ were significantly lowered in the control( P<0.05).The observation group before and after treatment, serum CD4+,CD4+/CD8+  had no significant change(P>0.05).After treatment,serum CD4+,CD4+/CD8+ in the control group was lower than the observation group(P<0.05).Serum IgG,IgA,IgM,IgE of the control group were significantly lowered(P<0.05).Serum IgG,IgA,IgM,IgE of the observation group had no significant change(P>0.05).The two groups after treatment group,serum IgG,IgA,IgM,IgE decreased more significantly in the control( P<0.05).Conclusion:Leukoreduced blood transfusion had smaller effects on immune function in patients.

2015 Vol. 12 (11): 104-106 [Abstract]( 619 HTML (1 KB)  PDF  (672 KB)  ( 225 )

XIAO Xiong-sheng,ZHANG Zhi,ZHANG Yuan-qi,et al.

Objective:To study the surgical techniques,complications and clinical significance of ultrasoundguided internal jugular vein implantation of access port(IVAP).To assess the safety and feasibility of the access port.Method:The clinical data 196 cases breast cancer patients who implanted IVAP from January 2013 to June 2014 in our hospital were analyzed retrospectively.Result:The success rate of first puncture in this group of patients was 100%,the catheter tip was located between the 4-6 T in the chest radiograph.There were no pneumothorax, hemothorax, arterial puncture,arrhythmia,hematoma,gas embolism and other complications in the patients.5 cases of neck discomfort and a sense of pulling.The catheter into the angle in 1 cases(through the left internal jugular vein), 3 cases finded the catheter distort in the injection seat at the connection.No patient removed transfusion port because of complications. Conclusion:Ultrasound-Guided Insertion of Implantable venous access port through Internal jugular vein is safe and effective, simple and feasible,can reduce the pain of patients, improve the patient’s quality of life.So it is worthy of promotion in clinical work.

2015 Vol. 12 (11): 107-110 [Abstract]( 835 HTML (1 KB)  PDF  (703 KB)  ( 902 )

JIA Hong-long.

Objective:To investigate the relation between the amount of HBV-DNA in serum of patients with HBV infection and the marker of hepatitis B virus.Method:Serum HBV-DNA was quantitatively detected by tiny plank nucleic acid hybridize technique of PCR to 200 policlinic patients infected with HBV and 20 healthy men.Result:The men were divided into 5 groups with the marker of HBV, there were significance differences from student test between HBsAg, HBeAg, HBcAb masculine and others.Conclusion:It is as index that the marker of HBV monitor hepatitis B virus infection, which couldn’t reflect completely replication of HBV.Quantitative detection of HBV-DNA had important significance to moniter the state of HBV infection and drug treatment.

2015 Vol. 12 (11): 110-112 [Abstract]( 486 HTML (1 KB)  PDF  (685 KB)  ( 418 )

YANG Jian-song.

Objective:To evaluate the clinical characteristics and MRI diagnostic value of hirayama disease.Method:Analyse the clinical and MRI feature of hirayama disease in 6 cases proved by clinical.Result:5 males and 1 female in 6 cases,with muscle weakness and atrophy on uooer limbs, 5 cases showed unilateral and 1 case showed bilateral but asymmetric involvement.In the flexion position MRI scan,the forwords movement of lower cervical cord and
the abnormal lunular signal with posterior epidural space in all cases.Conclusion:Hirayama disease occurs mainly in young males.The hirayama disease shows characteristic manifestations on the flexion position MRI appearance,which can help the doctor make diagnosis in the early stage.

2015 Vol. 12 (11): 113-116 [Abstract]( 657 HTML (1 KB)  PDF  (801 KB)  ( 231 )

CHEN Zu-yong,ZHAO Yan-qing.

Objective:To study the effect of risk management in the wards of neurology department.Method:70 cases of patients were selected to set control and observation group respectively, then compared the risk rate, satisfaction of patients and the quality of service of this two groups with before and after the implementation of risk management.Result:After implementing risk management in the wards of department of neurology, the risk rate was significantly lower than that of the control group.The degree of significant in the observation group was 87.1%, those in control group was 45.7%, showing significant difference.The quality of care increased remarkably when compared to control group.Conclusion:The implementation of risk management in the wards of neurology department can reduce the incidence of risk and improve the nursing quality and satisfaction of patients.

2015 Vol. 12 (11): 116-118 [Abstract]( 428 HTML (1 KB)  PDF  (671 KB)  ( 173 )

LI Hua-lian,WU Xiu-ru,ZHENG Ming-ying.

Objective:To investigate the risk factors and nursing countermeasures of catheter-associated urinary tract infection( CAUTI) among patients with indwelling catheter.Method:The incidence of CAUTI in 320 patients with indwelling catheter were observed,and its risk factors and nursing countermeasures were explored.Result:Among 320 patients with indwelling catheter,60 cases had CAUTI,the incidence rate was 18.75%.Logistic regression showed the risk factors of CAUTI were age,gender,time of indwelling catheter and bladder irrigation.Conclusion:The incidence rate of CAUTI is still at a high level in patients with indwelling catheter.Nurses must take proper measures to prevent and reduce the incidence of CAUTI.

2015 Vol. 12 (11): 119-121 [Abstract]( 642 HTML (1 KB)  PDF  (670 KB)  ( 353 )

YU Min,LI Na.

Objective:To compare the efficacy of holmium laser and pneumatic lithotripsy in the treatment of ureteraI calculi.Method:260 patients with ureteral calculi of our hospital from June 2012 to June 2014 were divided into two groups, the experimental group patients were given holmium laser lithotripsy, the control group patients were given pneumatic lithotripsy.Result:Operation time of the experimental group were lower than the control group(P<0.05), the disposable gravel success rate of two groups were 92.5% and 86.4%(P<0.05), the stones drained rate were 97.8% and 88.0%(P<0.05), and the complication rate of two groups were 5.0% and 16.0%( P<0.05).Conclusion:The effect of holmium laser lithotripsy under ureter mirror is better than that of pneumatic ballistic lithotripsy,it is worth popularizing in clinical application.

2015 Vol. 12 (11): 122-124 [Abstract]( 533 HTML (1 KB)  PDF  (671 KB)  ( 300 )

QIU Xiang,CAO Wei-juan,SHI Xiao-hong.

Objective:To analyze causes of insufficient blood volume in volunteer blood donors,seek to improve solution measures.Method:From January 2013 to July 2014,307 cases of insufficient volume blood in 101 619 voluntary blood donors come into being the cause of analyses and statistics.Result:Incidence of deficiency of blood collection was 0.302%,which proportion of deficiency cause by a reaction of 0.133%,see needles and other reasons causing the deficiency rate was 0.169%.Teams lack of voluntary unpaid blood donation amount less proportion of voluntary unpaid blood donation shortage.Insufficient flow of voluntary unpaid blood donation ratio higher than that of blood donation.Conclusion:Providing a good environment for blood donation,improved puncture technique of blood nurse ,prevention and reaction ,to reduce the amount of enough blood from source .

2015 Vol. 12 (11): 125-127 [Abstract]( 486 HTML (1 KB)  PDF  (674 KB)  ( 431 )

XIE Rui-wei.

Objective:To analyze the clinical effect of captopril sublingual administering and nitroglycerin emergency treatment intravenous drip in hypertension.Method:From February 2011 to October 2011, 76 cases of hypertension patients in emergency department of our hospital,76 patients were divided into two groups at random,the control group only sublingual administering captopril treatment,observation group with captopril joint nitroglycerin sublingual administering intravenous drip for treatment.Result:25 cases were markedly improved in observation group 38 cases,11 cases effectiveness and 2 cases, the total effective rate was 94.7%,the control group of 38 cases,20 cases were markedly effective,10 cases effectiveness and 8 cases, the total effective rate was 78.9%, two groups of patients with clinical effect contrast, significant difference was statistically significant( P < 0.05).Conclusion:The sublingual captopril administering and nitroglycerin intravenous drip,and in the clinical treatment of patients with hypertensive emergency treatment effect is good,and very convenient,safe,and suggest that clinical popularization and application.

2015 Vol. 12 (11): 127-129 [Abstract]( 500 HTML (1 KB)  PDF  (674 KB)  ( 344 )

XIAO Yuan-ling,LUO Zhi-ju,LIU Ting-ting,et al.

Objective:To investigate the clinical effect of laparoscopic resection combined with goserelin treatment in patients with uterine adenomyoma.Method:60 cases with uterine adenomyoma patients were selected in November 2012 to October 2014 in our hospital underwent laparoscopic lesions resection as the study object, the clinical data of all patients were reviewed and analyzed.Result:The uterine myoma patients after clinical treatment the strength and the amount of menstrual dysmenorrhea were significantly better than before the surgery,the differences had statistical significance(P<0.05);compared the menstrual cycle and the menstrual period before and after,the differences were no statistically significant(P<0.05).Conclusion:The application of laparoscopy lesion resection combined with goserelin in patients with uterine adenomyoma,it has significant effect.

2015 Vol. 12 (11): 129-130 [Abstract]( 496 HTML (1 KB)  PDF  (652 KB)  ( 294 )

DU Xiao-li.

Objective:To investigate the clinical efficacy of recurrent spontaneous abortion( RSA) using lymphocytes active immunotherapy.Method:80 cases of patients with RSA which were diagnosed by blocking antibody screening were randomly divided into the treatment group(40 patients) and the control group( 40 patients).The patients in the treatment group were treated by LIT with peripheral blood lymphocytes,the patients in the control group with traditional miscarriage treatment(progesterone plus hCG),then the pregnancy outcomes were compared.Result:In the treatment group,32 cases of pregnancy were treated successfully, and the success rate was 80%,including 16 patients with full-term delivery( 50%),16 cases with late pregnancy, 8 cases of abortion.In the control group,there were 16 cases with successful pregnancy,the success rate was 40%,including six cases with term birth(37.5%),10 cases with late pregnancy,24 cases of abortion.By comparison,there was significant difference in the two groups(P<0.01).After immunotherapy,34 patients became positive blocking antibodies,including 29 cases of pregnancy success,a success rate of 85.3%;six cases of blocking antibodies were still negative, two cases with pregnancy success,the success rate was 33.3%,respectively,the difference there was statistically significant(P<0.05).Conclusion:Lymphocyte active immunotherapy which is used to treat RSA is safe,effective,and reliable clinical value.

2015 Vol. 12 (11): 131-133 [Abstract]( 484 HTML (1 KB)  PDF  (675 KB)  ( 256 )

MAO Xue-di.

Objective:To investigate the clinical anesthetic effect of remifentanil combined with sevoflurane and remifentanil combined with propofol in laparoscopic operation.Method: 80 cases of gynecological laparoscopic surgery patients were selected from November 2013 to Octomber 2014 in our hospital as the research object,and were randomly divided into the observation group and the control group,40 cases in each group.Patients in the control group were
treated by remifentanil combined with propofol anesthesia,the observation group patients were treated by remifentanil combination with sevoflurane.Result: After clinical treatment,directional force of recovery time,eye opening time,spontaneous breathing time and extubation time of two groups’ patients were analyzed,the differences had no statistically significant(P>0.05).Conclusion: In the process of the implementation of laparoscopic surgery,two kinds of anesthesia methods have their advantages and disadvantages,so you can choose a proper method of anesthesia according to the actual situation.

2015 Vol. 12 (11): 133-135 [Abstract]( 509 HTML (1 KB)  PDF  (685 KB)  ( 282 )

TU Qing-hua.

Objective:To study the effect of minimally invasive treatment to improve the therapeutic effect of department of hepatobiliary surgery.Method:To analysis the treatment effect of surg gynecot in minimally invasive with laparoscopic surgery and traditional open surgery in Surg gynecot for example.Result:The time of surgery,hemorrhagic in operation,recovery time gastrointestinal,hospital stay,the ratio of complications of laparoscopic surgery in Surg gynecot was obviously lower than traditional open surgery,the differences was significant(P<0.05).Conclusion:It is very significant for minimally invasive treatment to improve the therapeutic effect of department of hepatobiliary surgery.

2015 Vol. 12 (11): 135-136 [Abstract]( 478 HTML (1 KB)  PDF  (652 KB)  ( 177 )

ZENG Geng,CHENG Jin-hai,JIANG Shi-xiong,et al.

Objective:To study clinical application value and its influence of transurethral ureteroscopy and percutaneous nephroscope in ureteral calculi surgery patients.Method:A retrospective analysis of our hospital uropoiesis surgical department from January 2012 to July 2014 accepts treatment, the clinical data of 120 patients with ureteral calculi were randomly divided into experimental group and control group, experimental group of patients with urethral ureter mirror surgery method of treatment, the control group were treated by skin kidney surgery method of treatment the mirror, by observing two groups of patients with calculi clearance rate of adverse reaction operation time and operation expenses, etc.Result:Ureter mirror:the experimental group USES the urethra stone extraction for the cure rate of patients was obviously higher than that of control group, and the probability of adverse reactions are significantly lower than the
control group, shorter operation time, less operation cost, the patient’s recovery was good, but the control group of stone clearance rate higher than that of the experimental group, whereas the control of operation time was long, the high cost of operation, the difference was statistically significant(P<0.05).Conclusion:Ureteroscopy take urethral stone with high cure rate Less adverse reaction Recovery time is short high safety, can effectively reduce the incidence of serious complications, the patients treated with percutaneous nephroscope calculi clearance rate is high, but the operation time is long, the high cost of operation, therefore, before the surgery should be the best treatment for different patients take corresponding measures, in order to improve the success rate of surgery.

2015 Vol. 12 (11): 137-139 [Abstract]( 558 HTML (1 KB)  PDF  (682 KB)  ( 318 )

LI Yang,CHEN Wei-yuan,ZHANG Cai-ling.

Objective: To study the effect of pain degree of patients after radical operation for carcinoma of stomach by using two ways of general anesthesia and spinal anesthesia combined with epidural anesthesia. Method: 64 cases of the patients underwent radical operation for gastric cancer in our hospital were selected and randomly divided into two groups, the observation group and the control group, 32 cases in each group. The patients in control group were underwent the radical operation for carcinoma of stomach with general anesthesia while the observation group with spinal anesthesia combined with epidural anesthesia. At different time after the operation the pain degree of patients were evaluated and the evaluation results in two groups were compared. Result: The postoperative pain score of 1 h in two groups had no statistical significance(P>0.05). And the comparison of the pain scores at different time points of postoperative 4, 8, 12, 24 and 48 h , the difference was statistically significant(P<0.05).Conclusion:Patients of the radical operation for carcinoma of stomach, using spinal anesthesia combined with epidural anesthesia is more conducive to the control of postoperative pain, has great significance for improving the quality of life of patients, which is worthy of clinical use and reference.

2015 Vol. 12 (11): 140-142 [Abstract]( 482 HTML (1 KB)  PDF  (671 KB)  ( 228 )

XU Xiao-fen,LIAO Yu-xin,HUANG Rui-lian.

Objective: To investigate the application effectiveness and safety inquiry of patients with cesarean section scar pregnancy treated with vaginal surgery. Method: 30 cases of patients with cesarean section scar pregnancy were chosen from January 2011 to August 2013 in our hospital to received treatment,and divided into observation group and control group,15 patients in each group. The effects and complications were analyzed.Result: After treatment,analyzed the efficacy of observation group and the control group, the success rate was respectively 93.3% and 66.7%,after a comparative analysis, the difference was statistically significant( 字2=6.282,P<0.05).After treatment, analyzed after comparative analysis the amount of bleeding,length of stay and β-hCG in the observation group and the control group of patients,the differences were statistically significant( P<0.05).30 cases of CSP patients after treatment, 28
cases of patients were able to complete the preserve fertility. In the followed-up process, the blood β-hCG value of the observation group was able to quickly return to normal; the control group patients after the weekly review, blood β-hCG values in 12 patients 1-5 weeks after discharge can be restored normal. 25 patients were in the 30-40 d menstrual cramps,5 patients were in the 40-60 d menstrual cramps.Conclusion: After vaginal surgery for the treatment of patients with caesarean section scar pregnancy is a more appropriate treatment, but for the patients of vaginal stenosis, cervical difficult to expose, should be based on the actual situation, through the vaginal ultrasound and surgical experience of physicians,to take reasonable treatment programs and provide protection for the rehabilitation of patients.

2015 Vol. 12 (11): 143-145 [Abstract]( 575 HTML (1 KB)  PDF  (672 KB)  ( 263 )

ZENG Jian-sheng.

Objective:To discuss the clinical application effect of caffeine cit rate combined with BiPAP ventilation in treatment of premature infants with apnea.Method:30 cases of apnea of prematurity were selected in our hospital from January 2013 to June 2014,they were randomly divided into the observation group and the control group,the control group choose caffeine cit rate treatment,and the observation group choose caffeine cit rate combined with BiPAP ventilation therapy.Result:Total effective rate in the control group was 66.7%;while the total efficiency in the observation group was 93.3%,the clinical therapeutic effect in the observation group was significantly higher than that of the control group( P < 0.05).Conclusion:For apnea of prematurity,application of caffeine citrate combined with BiPAP ventilation therapy with implementation of clinical effect is very significant,which is worth being popularized and used in clinic.

2015 Vol. 12 (11): 146-147 [Abstract]( 553 HTML (1 KB)  PDF  (652 KB)  ( 215 )

HUANG Wei-qiong,HUANG Zhi-qiang.

Objective:To investigate the application of hypertension patients sinistral amlodipine joint treatment the clinical effect of atorvastatin calcium tablet.Method:140 cases of patients with high blood pressure can be divided into two groups at random, 70 cases in each group.Amlodipine group application joint atorvastatin calcium treatment,control group nifedipine retard-20 tablet treatment,compared two groups of patients before and after treatment the blood,heart rate,and the change of quality of life.Result:After treatment,the observation group total effective rate(97.14%) were significantly better than the control group(87.14%), statistically significant difference(P<0.05).Conclusion:Using amlodipine in combination with atorvastatin calcium treatment of high blood pressure, heart rate,blood pressure can obviously improve patients such as indicators, relieve symptoms, improve the patients quality of life,clinical effect is remarkable, is worth popularizing in clinical application.

2015 Vol. 12 (11): 148-149 [Abstract]( 746 HTML (1 KB)  PDF  (652 KB)  ( 496 )

CAI Ye-yan,SUN Xiao-chuan.

The intracranial aneurysm is the most common cause of traumatic subarachnoid hemorrhage.Intracranial aneurysm rupture again after the patient’s mortality, so how to early diagnosis of a matter of concern to the clinician.In recent years, with the CTA and DSA examination technology such as the development of intracranial aneurysm detection rate has increased.At present, the CTA as relatively noninvasive examination method, play an important role in the diagnosis of intracranial aneurysms.This article will review value to the diagnosis of intracranial aneurysms CTA imaging technology and related research progress.

2015 Vol. 12 (11): 150-152 [Abstract]( 386 HTML (1 KB)  PDF  (694 KB)  ( 283 )

WEI Pei-jian.

Hand-foot-mouth disease(HFMD) is a common infection disease in preschool children,it is usually caused by enterovirus 71 and coxsackievirus A16. HFMD had aroused peoples wide attention because the clinical features of involving wide area and much population.It has been noted that enterovirus 71 infection is more severe with serious complications and fatality.The progress on the prevent measures and treatment will be reviewed,and provide a theoretical basis for clinical prevention and treatment for HFMD.

2015 Vol. 12 (11): 153-156 [Abstract]( 526 HTML (1 KB)  PDF  (704 KB)  ( 466 )

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