Objective：To explore the clinical value of preoperative endoscopic ultrasound（EUS）combined with MRI for prediction of TN stage of gastric cancer before operation.Method：31 case of pathologically confirmed gastric carcinoma were selected from May 2014 to August 2015，they received preoperative endoscopic ultrasound（EUS）combined with MRI for prediction of TN stage.The pathological TN stage was regarded as the gold standard.The coherence of preoperative signs on combined EUS and MRI scan was compared with the gold standard.Result：Compared with histopathologic results， the coherence rates of T and N stage in EUS combined with MRI scan all were 80.6%，the result had a good coherence（ Kappa=0.65，P<0.05）.Conclusion：As a conclusion，combined EUS and MRI has a high predictive value for TN stage of gastric cancer before operation.

2017 Vol. 12　(29):　6-8 [Abstract]（ 2070 ） HTML (1 KB)  PDF  (995 KB)  ( 534 )

Objective：To investigate the expression of MUC2 in normal colorectal tissue，colorectal adenomas and colorectal carcinomas，and to explore the relation between the expression of MUC2 and its associated clinical data. Method：15 cases of normal colorectal tissues，41 cases of colorectal adenomas tissues and 121 cases of colorectal carcinomas tissues in our hospital were selected from March 2011 to March 2015.The expression of MUC2 in different tissues were detected by immunohistochemistry. Result：（1）The positive expression rates of MUC2 in normal colorectal tissues，colorectal adenomas tissues and colorectal carcinomas tissues were 100%（15/15），73.17%（30/41） and 46.28%（56/121） respectively.The differences of the positive expression rates in different tissues were statistically significant（P<0.01）.（2）The histological differentiation，lymph node metastasis and tumor stage in patients with high expression rates of MUC2 were better than those in patients with low expression rates of MUC2，the differences were statistically significant（P<0.05）. Conclusion：The expression of MUC2 in colorectal carcinomas has relationships with histological differentiation，lymph node metastasis and tumor stage.The down-regulation of MUC2 expression may play a role in the carcinogenesis，progression，infiltration，metastasis and other processes of colorectal carcinomas.

2017 Vol. 12　(29):　12-14 [Abstract]（ 1834 ） HTML (1 KB)  PDF  (1406 KB)  ( 659 )

Objective：To analyze the positive rate and clinical significance of incomplete antibody after repeated transfusion. Method：1600 people with repeated blood transfusion in our hospital from June 2013 to March 2015 were selected as the observation group.1600 people who received blood transfusion for the first time were selected as the control group at the same time.The incomplete antibody in the blood samples of the two groups were screened.The positive rate of incomplete antibody and its relationship with adverse reactions of blood transfusion were observed.The antibody types of the observation group were analyzed，the positive situation of anti-D，autoantibodies，anti-Ec，anti-C，anti-c，anti-e，anti-M，anti-JKa and unknown antibody in patients with different blood transfusion times were observed. Result：The positive rate of incomplete antibody in the observation group was significantly higher than that in the control group，the difference was as statistically significant（ P<0.05）.The positive rates of incomplete antibody in patients with 3 to 5 times and 6 to 10 times of blood transfusion were lower than that in patients with more than 15 times of blood transfusion，the differences were statistically significant（P<0.05）.The adverse reaction of blood transfusion in patients with positive incomplete antibody was higher than that in patients with negative incomplete antibody，the difference was statistically significant（ P<0.05）.In the observation group，patients with 3 to 5 times of blood transfusion had 3 kinds of antibodies，patients with 6 to 10 times of blood transfusion had 4 kinds of antibodies，patients with 11 to 15 times of blood transfusion had 6 kinds of antibodies，patients with more than 15 times of blood transfusion had 7 kinds of antibodies. Conclusion：According with the increasing of the times of transfusion，the occurrence rates of positive incomplete antibody and the adverse reaction of blood transfusion increase，the kinds of antibodies also increase. The times of blood transfusion shall be controlled in order to ensure the better effect of blood transfusion.

2017 Vol. 12　(29):　21-24 [Abstract]（ 1724 ） HTML (1 KB)  PDF  (1074 KB)  ( 531 )

Objective：To study the correlation between obstructive sleep apnea hypopnea syndrom and throat reflux at night. Method：58 patients with OSAHS in our hospital from September 2012 to September 2013 were selected as the research objects. The situation of sleep all night，the pH of the throat and the esophagus pressure were monitored.The relationship between OSAHS and LPR was analyzed. Result：Among the 58 patients，a total of 17 patients were with LPR.In the LPR patients，the severity of OSAHS had a negative correlation with the average pH of the throat（P<0.05）. The average pressure and the minimum pressure of the esophageal in patients with LPR were lower than those in patients without LPR，the differences were statistically significant（P<0.05）. The AHI，AHTI and non-central AHTI had a negative correlation with the average pressure of the esophageal all night（P<0.05）. Conclusion：Severity OSAHS patients is closely related to the throat reflux happened at night.OSAHS patients prone to occurring gastroesophageal reflux，which resulting in a decline in pH value of the throat.

2017 Vol. 12　(29):　27-29 [Abstract]（ 1380 ） HTML (1 KB)  PDF  (1082 KB)  ( 648 )

Objective：To compare the clinical curative effects of simple decompression and fusion operation for the treatment of lumbar spondylolisthesis patients. Method：The clinical data of 63 patients with lumbar spondylolisthesis in our hospital underwent decompression or fusion operation treatment from March 2008 to June 2014 were retrospectively analyzed.According to the different surgical procedures，they were randomly divided into 31 cases with simple decompression surgery（the decompression group） and 32 cases with decompression joint fusion surgery（the fusion group）.The average follow-up was 4.5 years（1-6 years）.The general data，imaging data and surgical data of the two groups were retrospectively observed. Result：There were no statistically significant differences in the age，followup time，surgical procedure，ASA grading and preoperative conditions between the two groups（P>0.05）.At the last follow-up，the correction of lumbar lordotic angle（determined radiologically） was significantly better than the fusion group，the difference was statistically significant（P<0.05）.However，clinical outcomes including visual analogue scale，Oswestry Disability Index，and the Odom’s criteria，there were no statistically significant differences between the two groups（P>0.05）.The operation time，hospitalization time，intraoperative bleeding volume and operative complications of the decompression group were significantly better than those of the fusion group，the differences were statistically significant（P<0.05）.Conclusion：Screw rod fusion surgery after decompression effect is better，simple laminectomy has less trauma，two kinds of operation modes have their own advantages and disadvantages，but fusion operation is better.

2017 Vol. 12　(29):　34-37 [Abstract]（ 1416 ） HTML (1 KB)  PDF  (1130 KB)  ( 371 )

Objective：To investigate the prevention value for patients with deep vein thrombosis after general surgery detected by D- dimer（ D-Dimer，DD） and coagulation factor. Method：48 inpatients with general surgical from January 2014 to January 2015 in our hospital were selected and divided into without deep vein thrombosis group for 32 cases（ non-DVT group）and deep vein thrombosis group for 16 cases（ DVT group）.D-D and fibrinogen（ FIB） in blood were detected respectively before surgery and after surgery of 1 day，3 and 7 days. Result：D-D and FIB levels of patients in two groups at first and third day after surgery were significantly increased， compared with before surgery the differences were statistically significant（P<0.05）. D-D and FIB levels in the non-DVT group at the 7th day after surgery decreased to the preoperative level，compared with before surgery the differences were no statistically significant（P>0.05）. The D-D and FIB levels at the 7th day after surgery in the DVT group were significantly increased，compared with the preoperation，the differences were statistically significant（P<0.05）.Conclusion：Determination of D-dimer and coagulation factor have better preventive values for deep vein thrombosis after general surgery，it is worthy of clinical promotion.

2017 Vol. 12　(29):　42-45 [Abstract]（ 1329 ） HTML (1 KB)  PDF  (1103 KB)  ( 363 )

Objective：To investigate the feasibility and safety of multifunctional endoscopic mask oxygen inhalation technology in elderly chronic obstructive pulmonary disease（COPD） patients with the examination of painless gastroscopy.Method：66 patients with COPD in stable phase were selected and randomly divided into the multifunctional endoscopic mask group（group A） and the nasal catheter group（group B），33 cases in each group，all patients were given the examination of painless gastroscopy.The group A was given multifunctional endoscopic mask oxygen inhalation，the group B was given nasal catheter oxygen inhalation.The systolic pressure，diastolic pressure，heart rate and pulse oxygen saturation of the two groups were observed and compared before giving oxygen（T0），after anesthesia and before the examination（T1），during the examination（T2） and after the examination（T3）.The total time of the examination，the times of SpO2<90% and SpO2<80% and the situation of interrupt check were recorded and compared between the two groups.Result：The differences in heart rate and blood pressure of different time between group A and group B were not statistically significant（P>0.05）.In the time of T1，T2 and T3，the values of SpO2 in group A were significantly higher than those in group B.The times of SpO2<90% and SpO2<80% in group A were less than those in group B.The situation of interrupt check and the total time of examination in group A were better than those in group B.The differences above were all statistically significant（P<0.05）.Conclusion：Multifunctional endoscopy mask in elderly COPD patients with the examination of painless gastroscopy can improve patients’ SpO2 and shorten the examination time.It is a safe and effective auxiliary tool of anesthesia.

2017 Vol. 12　(29):　49-51 [Abstract]（ 1311 ） HTML (1 KB)  PDF  (1052 KB)  ( 528 )

Objective：To analyze the currant situation of repeated cesarean section in primary hospitals and discuss the measures to further reduce the rate of cesarean section.Method：The clinical data of 981 puerperae who had repeated cesarean section admitted to our hospital from 2011 to 2013 were retrospectively analyzed，the changes of repeated cesarean section rates and indications in different periods were statistically analyzed.Result：The repeated cesarean rates of our hospital were 93.64 %，47.30%，76.08% in 2011，2012 and 2013.The average cesarean section rate was 72.34%.The top five of the cesarean section indications were tubal ligation，social factors，preeclampsia，fetal distress，abnormal stage of labor.Conclusion：High repeated cesarean section rate is caused by many factors.It can be reduced by updating the conception of obstetricians and pregnant women，enhancing the propaganda of perinatal health care，encouraging vaginal birth after cesarean section，improving professional skills of midwives and so on，so as to reduce the risk of mother and son from cesarean delivery operation.

2017 Vol. 12　(29):　55-58 [Abstract]（ 1230 ） HTML (1 KB)  PDF  (1143 KB)  ( 377 )

Objective：To observe the effect of lipid-lowering therapy on pulse wave velocity in patients with mild to moderate hypertension and to explore its mechanism.Method：120 mild to moderate hypertension patients without hyperlipidemia in our hospital from February to October 2013 were selected and randomly divided into the control group and the lipid-lowering group，each group had 60 patients.All patients of the two groups were given Nifedipine and Valsartan to control the blood pressure，the lipid-lowering group was given Atorvastatin to reduce lipid on the basis of the above treatment.The therapeutic course was 12 months.The blood pressure，brachial ankle pulse wave velocity（ baPWV），blood lipid levels，high sensitive C reactive protein（hs-CRP） and endothelin（ET） of the two groups were detected and compared before and after treatment.Result：Before treatment，the levels of baPWV，ET and hs-CRP of the two groups were all higher than the normal ranges，the differences were statistically significant（P<0.05）.The levels of SBP，DBP，baPWV，ET and hs-CRP of the two groups after treatment were all better than those before treatment.The levels of TC and LDL-C of the lipid-lowering group after treatment were better than those before treatment.The levels of TC，LDL-C，baPWV，ET and hs-CRP of the lipid-lowering group were better than those of the control group.The differences above were all statistically significant（P<0.05）. Conclusion：For patients with mild to moderate hypertension，antihypertensive combined with lipid-lowering therapy can decrease the levels of baPWV，hs-CRP and ET obviously.It has a positive clinical significance in improving the state of vascular function.

2017 Vol. 12　(29):　62-65 [Abstract]（ 956 ） HTML (1 KB)  PDF  (1151 KB)  ( 420 )

Objective：To compare the efficacy and safety of Rabeprazole-based 10-days sequential therapy including Rabeprazole，Amoxicillin，Clarithromycin，Furazolidone，with 10-days standard triple therapy including Omeprazole，Amoxicillin，Furazolidone in Helicobacter pylori.eradication.Method：A total of 160 Helicobacter pylori patients with infection in active peptic ulcer were recruited and randomly assigned into the treatment group and the control group，80 cases in each group.The treatment group（sequential therapy） was implemented with RA program which included orally taking Rabeprazole 10 mg per time，Amoxicillin 1000 mg per time，twice per day in the first five days，after the five days，the treatment group was implemented with RCF program which included orally taking Rabeprazole 10 mg per time，Clarithromycin 500 mg per time，Furazolidone 100 mg per time，twice per day for five days，then the treatment group was given Rabeprazole 10 mg once per day for three weeks.The control group（standard triple therapy） was implemented with OAF program which included orally taking Omeprazole 20 mg twice per day，Amoxicillin 1000 mg twice per day，Furazolidone 100 mg twice per day for 10 days，then the control group was given Omeprazole 20 mg，once per day for three weeks.Four weeks after the completion of treatment，the efficacy and safety were evaluated by gastroscopy，rapid urease test and 14C urea breath test were determined for Helicobacter pylori.Result：A total of 156 patients completed the treatment.With intention-to-treat（ITT） analysis，the Helicobacter pylori eradication rate in the treatment group was 92.50%（74/80），which was significantly higher than 78.75%（63/80） of the control group，the difference was statistically significant（ χ²=19.262，P<0.01）.With per protocol（PP） analysis，the Helicobacter pylori eradication rate in the treatment group was 94.87%（74/78），which was significantly higher than 80.77%（63/78） of the control group，the difference was statistically significant（ χ²=15.566，P<0.01）.The incidence of adverse reaction rates of the treatment group and the control group were 18.75%（ 15/80） and 22.50%（18/80） respectively，there was no statistically significant difference（P>0.05）.Conclusion：The 10-days sequential therapy including Rabeprazole，Amoxicillin，Clarithromycin，Furazolidone is more effective than 10-days standard triple therapy including Omeprazole，Amoxicillin，Furazolidone in eradicating Helicobacter pylori，can achieve a very high rate of Helicobacter pylori eradication and good curative effect.The individual difference is small，the incidence of adverse reaction is low，the patients’ compliance is good，it is worthy to be popularized in clinic.

2017 Vol. 12　(29):　69-73 [Abstract]（ 1366 ） HTML (1 KB)  PDF  (1247 KB)  ( 264 )

Objective： To explore the value of real-time three-dimensional echocardiography to assess ventricular systolic function in patients with dilated cardiomyopathy.Method： 39 patients with DCM were selected as the study group in our hospital from March 2014 to May 2015， at the same time 39 cases healthy check-up as the control group，they were given real-time three-dimensional ultrasound and two-dimensional ultrasound checked， the two groups of patients with ventricular function parameters were compared.Result： The patients with left and right ventricular stroke volume in study group compared with those of control group， there were no statistically significant differences（ P>0.05）；the left and right ventricular ejection fraction in study group were lower than those of the control group， end-diastolic volume and end-contraction volume were higher than those of control group， the differences were statistically significant（P<0.001）. The study group patients with ventricular systolic function under the condition of 2D and 3D each indexes were statistically significant differences（P<0.01）；under the condition of 2D and 3D measurement of left and right ventricular ejection fraction was positively correlation（ r=0.65，P<0.01；r=0.67，P<0.01）.Conclusion：Real-time three-dimensional echocardiography can accurately evaluate left and right ventricular function in patients with DCM， it is worthy of clinical popularization and application.

2017 Vol. 12　(29):　77-79 [Abstract]（ 1076 ） HTML (1 KB)  PDF  (1101 KB)  ( 232 )

Objective：To observe the curative effect and adverse reactions of the re-radiotherapy in recurrence from esophageal carcinoma after radiotherapy.Method：From November 2013 to July 2014，32 patients were hospitalized to accept the treatment of re-radiotherapy because of the recurrence from esophageal carcinoma after radiotherapy，including 24 cases of conventional radiotherapy，8 cases of three dimensional conformal radiotherapy，a median dose was 64 Gy，3 patients underwent radiotherapy combined with chemotherapy，TP regimen，4 cases were given local dilatation therapy for endoscopic treatment under gastroscope.The treatment effect and adverse reactions of all patients were observed.Result：The short-term curative efficiency was 62.5%，the incidence rate of radiation esophagitis was 68.8%，the incidence rate of radiation pneumonitis was 46.9%，and the incidence rate of myelosuppression was 65.6%.Followed up to December 2014，four patients died（ 12.5%）. Conclusion：In the retreatment of the recurrence from esophageal carcinoma after radiotherapy，radiation therapy is a more effective approach，it is recommended to use of the 3DCRT or IMRT technology，while in the process of re-radiotherapy combined with chemotherapy，the side effect of chemotherapy with radiotherapy is obviously increased，it should be particularly cautious.

2017 Vol. 12　(29):　83-86 [Abstract]（ 1104 ） HTML (1 KB)  PDF  (1184 KB)  ( 618 )

Objective：To investigate the application of hydrocolloid dressings in the neonatal noninvasive assisted ventilation.Method：A total of 200 newborns with noninvasive assisted ventilation admitted to our hospital from February 2011 to February 2014 were selected as research objects，they were divided into the observation group and the control group according to the random number table method，100 cases in each group.The control group was given conventional methods for treatment，the observation group was given hydrocolloid dressings on the basis of the control group.The ventilation effect，treatment compliance，skin damage of the children and the parents’ satisfaction with ventilation therapy between the two groups were compared.Result：After treatment，the ventilation treatment total effective of the observation group was 97.0%，which was significantly higher than 84.0% of the control group，the excellent rate of treatment compliance in the observation group was 88.0%，which was significantly higher than 70.0% in the control group，the incidence of skin damage in the observation group was 2.0%，which was significantly lower than 16.0% in the control group，the parents’ satisfaction with ventilation therapy of the observation group was 98.0%，which was significantly higher than 70.0% of the control group，the differences were statistically significant（P<0.05）.Conclusion：The application effect of hydrocolloid dressings in neonatal noninvasive assisted ventilation is significant，is worthy of promotion and application in clinical research and treatment

2017 Vol. 12　(29):　90-93 [Abstract]（ 1037 ） HTML (1 KB)  PDF  (1236 KB)  ( 379 )

Objective：To introduce design and production methods of a kind of maternal multifunctional convenient pants and observe the effect of clinical application. Method：The specific production method of a kind of maternal multifunctional convenient pants was introduced.The experimental group and control group were set up in clinic，50 cases in each group.The experimental group was given new-style maternity pants，and the control group was given oldstyle pants.The use effects of new type of maternity pants were evaluated.Result：The perineal nursing operation time of the experimental group was significantly shorter than the control group，the effects of indwelling catheter fixation，sand fixation and reyanbao fixation were significantly better than those in the control group，the proportion of "good" of maternal and medical staff satisfaction in the experimental group were 88.00% and 96.00%，which were significantly higher than 32.00% and 18.00% in the control group， the differences were statistically significant（P<0.001）. Conclusion：The new maternal multifunctional convenient pants is convenient for nursing operating and treatment，which can reduce the work intensity and improve satisfaction of nurses and doctors，and is worthy of clinical promotion.

2017 Vol. 12　(29):　97-100 [Abstract]（ 1375 ） HTML (1 KB)  PDF  (1789 KB)  ( 346 )

Objective：To observe clinical influences of Liuwei Dihuang Pills combined Traditional Chinese Medicine（ TCM） inunction on postoperative recovery of lumbar intervertebral disc protrusion， and provide theoretical basis for TCM combined with Western Medicine treatment in later periods.Method：From December 2013 to December 2014，68 postoperative patients were selected with lumbar intervertebral disc protrusion admitted by the orthopedics department combining TCM and Western medicine， and they were divided into two groups depending on postoperative treatment，34 patients in control group received conventional Western medicine treatment， and 34 patients in research group were treated combined therapy of TCM inunction and Liuwei Dihuang Pills. Clinical efficacy， JOA score， quality of life score，VAS pain score and adverse reactions of patients between the two groups were compared.Result：The total effective rate of the research group was relatively higher than that of the control group， but the rate of adverse reactions was lower， and the differences were statistically significant（P<0.05）.The JOA scores of the research group were higher than those of the control group，the differences were statistically significant（P<0.05）.The VAS score before and after treatment of the two groups showed statistically differences（P<0.05），and those of the research group after treatment were lower than those of the control group（P<0.05）.After treatment，the QLO-C30 life quality scores of the research group were higher than those of the control group，and the differences were statistically significant（P<0.05）.Conclusion：Liuwei Dihuang Pills combined TCM deliver great treatment efficacy for the treatment of postoperative lumbar disc protrusion when compared to conventional Western medicine treatment， improve postoperative pain and lumbar function of patients， and the patients quality of life， and impose low rate of adverse reactions， being worthy of clinically safe and effective way to promote.

2017 Vol. 12　(29):　110-113 [Abstract]（ 1282 ） HTML (1 KB)  PDF  (1287 KB)  ( 516 )

Objective：To study and analyze the clinical effect of vertebral pedicle screw by paraspinal approach in the treatment of patients with thoracic and lumbar fractures.Method：66 patients with thoracic and lumbar fractures in our hospital from January 2013 to June 2014 were selected as research objects，and all the patients were divided into the control group（conventional operation by posterior approach group） and the observation group（vertebral pedicle screw by paraspinal approach group） according to the operation methods，33 cases in each group.Then the operation time，intraoperative blood loss，postoperative pain state and related parameters of vertebral body before and after the operation of the two groups were respectively analyzed and compared. Result：The operation time of the observation group was significantly shorter than that of control group，the intraoperative blood loss was significantly less than that of control group，the postoperative pain degree was significantly lighter than that of control group，the related parameters of vertebral body 1 month and 6 months after the operation were all significantly better than those of control group，the differences were statistically significant（P<0.05）. Conclusion：The clinical effect of vertebral pedicle screw by paraspinal approach in the treatment of patients with thoracic and lumbar fractures is better，and its comprehensive application value is higher.

2017 Vol. 12　(29):　117-119 [Abstract]（ 1047 ） HTML (1 KB)  PDF  (1186 KB)  ( 334 )

Objective：To study the feasibility of mobile internet of things in postoperative analgesia management. Method：100 patients who needed analgesia after cesarean section from May 2014 to November 2014 were selected as the research objects.They were divided into two groups，each group had 50 patients.The control group was given analgesia management through traditional electronic analgesic pump，while the observation group was given analgesia management through the mobile internet of things.The scores of analgesia，the processing time of alarm events and patients’ satisfaction were recorded and compared between the two groups.Result：The differences in NRS scores and complications of postoperative analgesia of the two groups were not statistically significant（P>0.05）.The processing time of alarm events of the observation group was shorter than that of the control group.The satisfaction score and satisfaction rate of the observation group were higher than those of the control group.The differences above were all statistically significant（P<0.05）. Conclusion：The management of related events of analgesic pump and medical workers’ management and service are the important reasons which influence the total satisfaction of postoperative analgesia.The mobile internet of things used in postoperative analgesia management can improve medical workers’ work efficiency，enhance patients’ satisfaction and make the doctor easier.It conforms to the requirements of the transformation of medical service mode and the development of era.It is worthy of clinical extension and application.

2017 Vol. 12　(29):　123-126 [Abstract]（ 984 ） HTML (1 KB)  PDF  (1293 KB)  ( 282 )

Objective：To investigate the protection measures and clinical effects of spine stabilizing system of posterior reduction and internal fixation for the treatment of thoracolumbar fractures.Method：43 patients with thoracolumbar fractures who were treated with vertebral pedicle screw poking reduction and internal fixation admitted to our hospital from January 2010 to January 2013 were selected as research objects.They were divided into the modified paraspinal approach group（paraspinal approach group） for 23 cases and the traditional posterior median approach group（conventional approach group） for 20 cases according to the random number table method.The operative time，intraoperative blood loss，postoperative drainage volume，postoperative lumbar pain（VAS）and radiographic indexes between the two groups were compared.Result：Patients of the two groups were followed up for 12-18 months，The operative time of the paraspinal approach group was significantly shorter than the conventional approach group，the intraoperative blood loss and postoperative drainage volume of the paraspinal approach group were significantly less than the conventional approach group，the differences were statistically significant（P<0.05）.There was no statistically significant difference in the average VAS score before surgery（P>0.05）.The average VAS score of paraspinal approach group 3 days after surgery and the last follow-up were significantly lower than the conventional approach group，the differences were statistically significant（P<0.05）.Up to the last follow-up，the fracture vertebral height of two groups were no loss，no fracture internal fixation，vertebral height restoration in two groups were satisfied.Conclusion：The influence of modified paraspinal approach for the thoracolumbar spinal fracture to the paraspinal muscle is small，less complications，is conducive to the protection of spine stabilizing system，and there are synergistic effects with transpedicular screw fixation，can obtain good therapeutic effect.

2017 Vol. 12　(29):　130-133 [Abstract]（ 1255 ） HTML (1 KB)  PDF  (1333 KB)  ( 307 )

Objective：To analyze the clinical features， laboratory examination，imaging characteristics and diagnosis method of neurosyphilis.Method：23 patients with neurosyphilis were selected in No.1 People’s Hospital of Yangzhou from May 2009 to April 2015，the clinical features，laboratory examination， imaging characteristics，diagnosis and treatment of neurosyphilis were retrospectively analyzed.Result：The serum RPR and TPPA of all patients were positive，21 patients were positive with cerebrospinal fluid RPR and TPPA， 6 cases of cerebrospinal cell count increased，12 cases of the cerebrospinal fluid protein increased，the cerebrospinal fluid protein and white cell count was nomal had 5 cases.Among the 23 patients， 6 patients suffered dementia，11 cases suffered cerebral apoplexy，2 cases were neuralgia， 2 cases were epilepsy， 1 case was optic neuritis and 1 case was ataxia. The patients were no specifity MRI scanning，part of them showed cerebral infarctions，encephalatrophy，ventriculomegaly， varying degrees of cerebral white matter degeneration， gummatous abnormal signal or gyri enhancement and so on. Most of the patients showed obvious improvement in the symptoms after treated with penicillin or ceftriaxone.Conclusion： Neurosyphilis clinical manifestations are diverse and complex， part of them hidden but harm， combined with blood science，cerebrospinal fluid， and imaging examination are helpful to clinical diagnosis， timely and reasonable anti syphilis treatment can improve the prognosis.

2017 Vol. 12　(29):　136-138 [Abstract]（ 1126 ） HTML (1 KB)  PDF  (1664 KB)  ( 230 )

Objective：To observe the clinical curative effect of Xuesaitong combined with Troxerutin and Cerebroprotein Hydrolysate Injection for the treatment of ischemic cerebral apoplexy.Method：158 patients with ischemic cerebral apoplexy admitted to our hospital from January 2013 to June 2014 were selected，they were divided into the observation group and the control group according to the random number table method，79 cases in each group.The control group was given Troxerutin and Cerebroprotein Hydrolysate Injection for treatment，the observation group was given Xuesaitong combined with Troxerutin and Cerebroprotein Hydrolysate Injection for treatment.The neurological function defect situation before and after treatment，clinical efficacy and adverse reactions between the two groups were compared.Result：There were no statistically significant differences in neurological function defect score between the two groups before treatment（P>0.05），and the neurological function defect score of the observation group after treatment was obviously lower than the control group，the difference was statistically significant（P<0.05）.The total effective rate of the observation group was significantly 95.0%，which was significantly higher than 77.2% of the control group，the difference was statistically significant（P<0.05）.No adverse reactions occurred during the treatment of the two groups. Conclusion：Xuesaitong combined with Troxerutin and Cerebroprotein Hydrolysate Injection for the treatment of ischemic cerebral apoplexy can effectively improve the patients’ neurologic deficits，curative effect is distinct，less adverse reactions，is worthy of clinical popularization and application.

2017 Vol. 12　(29):　142-144 [Abstract]（ 1257 ） HTML (1 KB)  PDF  (1219 KB)  ( 233 )