Objective：To study the effect of siRNA-SIAH on α-synuclein autophagy and UPS degradation in SH-SY5Y.Method：After transfection of siRNA-FAM cells with fluorescent labeled SH-SY5Y， 3 siRNA were professional designed for SIAH，the protein level of SIAH expression was measured by Western Blot， one of the most efficient siRNA was selected.CCK-8 assay was used to detect the activity of siRNA-SIAH in SH-SY5Y cells. Flow cytometry was used to detect the apoptosis of siRNA-SIAH in SH-SY5Y cells.Western Blot was used to detect the protein level expression ofα-synuclein，LC3，E1，and P53.qRT-PCR was used to detect the level of mRNA in SIAH，α-synuclein，LC3 and E1. Confocal microscopy was used to detect the positioning of SIAH，α-synuclein and LC3-Ⅱ.Result： 3 siRNA cells successfully transfected SH-SY5Y，the transfection efficiency was 89%. The Western results showed that the expression of SIAH was significantly decreased in siRNA-2# cells， then studied this sequence. CCK-8 assay showed that the SH-SY5Y cell activity increased after siRNA interference， and the flow cytometry results showed that siRNA could inhibit the apoptosis of SH-SY5Y cells， which was significantly different from the control group and the negative control group（P<0.05）.With Western Blot method，the protein levels of α-synuclein， LC3 and P53 in siRNA-2# group were significantly lower and E1 was higher than that in control group and negative control group， the differences were statistically significant（P<0.05）.With qRT-PCR method，the mRNA level of SIAH，α-synuclein and LC3-Ⅱ mRNA in siRNA-2# group were significantly lower and E1 was higher than that in control group and negative control group，the differences were statistically significant（P<0.05）.Conclusion： Using siRNA to interfere with SIAH gene， SIAH gene can be used as a new target in the treatment of Parkinson’s disease by promoting the ubiquitin proteasome system to reduce SH-SY5Y in α-synuclein.

2015 Vol. 12　(27):　1-5 [Abstract]（ 612 ） HTML (1 KB)  PDF  (1079 KB)  ( 365 )

Objective： To investigate the relationship between muscle strength and injure time in the patients with anterior cruciate ligament rupture.To provide the basis for the choice of anterior cruciate ligament injury reconstruction operation time. Method：194 cases with unilateral ACL rupture were selected from January 2010 to Octomber 2013 as research objections.The PT value，PT/BW value，H/Q value and TW value of patients were obtained by isokinetic testing. The relationship between the injury time and these values was analyzed. Result：Compared with the healthy side， the PT value，PT/BW value and TW value of the injured side decreased significantly，the H/Q increased，the differences were statistically significant（P<0.01）.Injury time was associated with decreased muscle strength obviously， with the extension of injury time， flexor PT values gradually decline（ r=0.813；r=0.852）， compared four groups of flexor PT value，the differences were statistical significance（ P<0.05），within one month of flexor PT value was the highest.Conclusion： In patients with anterior cruciate ligament injury， muscle strength of injured limb would gradually declined according to the injure time. The surgery treatment of patients with anterior cruciate ligament injury should be taken within 1 month or in 3 months to 6 months when the muscle strength of the injured limb is better.

2015 Vol. 12　(27):　9-12 [Abstract]（ 744 ） HTML (1 KB)  PDF  (722 KB)  ( 420 )

Objective：To investigate whether FK1706 can promote the axon regeneration of peripheral nerve for rats after neural transplantation.Method：20 male SD rats were randomly assigned into two groups after they were performed with left sciatic nerve transection and autologous radial nerve grafting.Group A received FK1706（ 0.32 mg/kg） local intramuscular injected once a day on left lower limb for 8 weeks， while Group B as control were routinely fed without special intervention.Electrophysiological studies of left sciatic nerve were performed.The number and area of the regenerated myelinated nerve fiber in cross section pane， and wet muscle weight of the left gastrocnemius muscle were measured，respectively，at 8 weeks after operation.Result：The number of myelinated nerve fiber in proximal end， two groups has no significant difference in statistic（ P>0.05）， however， in distal end，number of myelinated nerve fiber in Group A was significantly higher than in Group B（P<0.01）. The thickness of myelin sheath（ mt） of the myelinated nerve fiber， and the ratio that bare axon diameter divided by the total fiber diameter（ d/D） were more favorable in Group A than the other， which difference has statistical significance（P<0.05）. The wet muscle weight of left gastrocnemius muscle， as well as the compound motor action potential（ CMAP） amplitude and motor nerve conduction velocity（ MNCV） in Group A，were much better than in Group B，with significant differences（ P<0.01）.Conclusion：FK1706 has neurotrophy effect that，
significantly promote neuroregeneration in rats after autologous nerve transplantation repairing surgery.

2015 Vol. 12　(27):　16-20 [Abstract]（ 752 ） HTML (1 KB)  PDF  (827 KB)  ( 232 )

Objective：To study the relationship between fetal growth restriction and umbilical blood flow and matelnal hematokrit.Method：64 pregnant women with fetal growth restriction in our hospital from April 2013 to December 2014 were selected as observation group，72 normal pregnant women were selected at the same period as control group. Umbilical blood flow ratio and matelnal hematokrit of the two groups were detected and compared.Maternal and fetal outcome were compared between two groups.Result：The abnormal rate and mean value of umbilical blood flow ratio in the observation group were significantly higher than those in the control group（P<0.05）.Matelnal hematokrit of the observation group was significantly higher than that of the control group（P<0.05）.Incidence of complications with pregnancy in the observation group were significantly higher than the control group（P<0.05）.Incidence of adverse maternal and fetal outcome in the observation group were significantly higher than those in the control group（P<0.05）.Conclusion：Fetal growth restriction has a close relationship with umbilical blood flow ratio and matelnal hematokrit，umbilical artery blood flow resistance and blood concentration can deteriorate fetal growth restriction，which will affect maternal and fetal outcome.

2015 Vol. 12　(27):　24-26 [Abstract]（ 664 ） HTML (1 KB)  PDF  (700 KB)  ( 238 )

Objective： To observe and study the clinical efficacy of combined uterine laparoscopy for the treatment of tubal blockage. Method： 64 patients who were treated for tubal blockage from June 2013 to June 2014 in our hospital were selected as the research subjects， they were randomly divided into two groups，the observation group and the control group， 32 cases in each group.The observation group was treated by combined laparoscopy and hysteroscopy，while the control group was treated with open surgery.The bleeding volume， operation time， length of stay， exhaust time， fallopian tube flow rate and success rate of pregnancy of the two groups were compared.Result： The intraoperative blood loss，operative time， hospital stay and exhaust time of the observation group were significantly lower than that of the control group， the differences were statistically significant（P<0.05）.The fallopian tube smooth rate of the observation group was 93.75%， the pregnancy success rate was 71.88%. while the tubal smooth rate of the control group was 75.00%， the pregnancy success rate was 46.88%.The fallopian tube flow rate and success rate of pregnancy of the observation group were significantly higher than those of the control group， the differences were statistically significant（P<0.05）. Conclusion： The clinical efficacy of hysteroscopy combined with laparoscopy for the treatment of fallopian tube blockage is obvious， the efficacy is significant， it is worthy of clinical application.

2015 Vol. 12　(27):　30-31 [Abstract]（ 598 ） HTML (1 KB)  PDF  (670 KB)  ( 287 )

Objective： To investigate the value of breast conserving therapy and sentinel lymph node biopsy（Sentinel lymph node biopsy， SLNB） in the treatment of early breast cancer. Method： 70 patients with early breast cancer were selected in our hospital， all of them had SLNB during breast cancer surgery， according to intraoperative sentinel lymph node（ Sentinel lymph node， SLN） rapid frozen section examination results， for SLN positive patients received breast conserving surgery modified radical mastectomy with standard axillary lymph node dissection（ Axillary lymph node dissection， ALND）， for SLN negative， then breast conserving combined with simplified ALND （only resection of pectoralis minor lateral group， Level Ⅰ）. Result： The simplify operation time， the patients hospitalization time， axillary drainage time was（ 75.51±6.65）min，（ 11.76±1.49）d，（ 3.92±0.61）d， the standard group was （117.60±5.46）min，（ 15.69±1.33）d，（ 7.65±0.53）d， the index had significant difference（ P<0.05）. The success rate of SLN biopsy was 100%. Among them， 25 cases were SLN positive， 45 SLN negative patients， the detection accuracy rate was 100%， false positive rate was 0. Postoperative clinical follow-up was 20-55 months for the patients with a mean follow-up of 42 months. The overall survival rate of the two groups after 3 year was both 100%， disease free survival rate was 100%. Conclusion： SLNB provides an important choice for the surgical treatment choices for early breast cancer.

2015 Vol. 12　(27):　35-37 [Abstract]（ 775 ） HTML (1 KB)  PDF  (692 KB)  ( 367 )

Objective：To evaluate the effect and safety of large dosage iodized oil（1ipiodol） treatment in huge primary hepatic carcinoma（PHC） via injecting from hepatic artery transarterial chemoembolization（TACE）. Method：One hundred sixty-six cases of huge PHC received 20 mL lipiodol or 25-45 mL lipiodol injection in each TACE.Tumor maximal diameter and liver function were recorded both before and after TACE.Angiography，lipiodol dosage and deposition in tumor and　complications　were also recorded.Result：All patients were followed-up 1 and 4 weeks after TACE respectively.The average dosage of large-lipiodol was 28.3 mL.Tumor maximal diameter was decreased[（13.15±5.32）cm vs（ 11.98±3.08）cm ].There was no statistical significance before and after operation in the two groups（P>0.05）.Some impairment of liver function was found in those patients after TACE 1 week.No major impairment of liver function was found in those patients after TACE 2 week.Median survival time of the conventional dose group were 6 months，while large dose group were 8 months.The survival rates of 6，12，18，24 months after treatment were 55.8%，32.2%，24.0%，13.7%.No severe complication happened in this series.The survival time of large dose group was longer than that of the conventional dose group， with statistical significance（P<0.05）. Conclusion：It is effective and safe for patients with huge primary liver cancer patients to receive high dose lipiodol TACE.The effect of large dose lipiodol treatment on mass hepatocellular carcinoma is superior to the common.

2015 Vol. 12　(27):　42-45 [Abstract]（ 699 ） HTML (1 KB)  PDF  (711 KB)  ( 288 )

Objective：To study the value of frequency domain OCT measurement of the thickness of retinal nerve fibrous layer and macular GCC in the diagnosis of primary glaucoma.Method：A total of 50 primary glaucoma patients in our hospital were selected as the experimental group，and 50 cases of normal eyes personnel during the same period in our hospital for physical examination were selected as the control group，clinical diagnosis effect of two groups were analyzed. Result： The RNFL average thickness around optic disc and average thickness of the macular region of GCC of two groups were significantly different（ P<0.05）.Conclusion：Application of frequency domain OCT detection of the thickness of fibrous layer and macular GCC in the diagnosis of primary glaucoma can objectively reflect the glaucoma optic nerve damage degree，have a higher value.

2015 Vol. 12　(27):　48-50 [Abstract]（ 656 ） HTML (1 KB)  PDF  (692 KB)  ( 471 )

Objective：To analyze the effect oflocking plate combined with allograft bone in extremities benign bone tumors with pathological fracture.Method：50 cases of long bones limbs benign bone tumors with pathological fracture were treated in our hospital from January 2013 to January 2015，and according to the different treatment methods，they were divided into study group（ 25 cases）， control group（ 25 cases）.The control group was treated with locking plate，the study group was treated with locking plate combined with allograft bone， clinical curative effect of two groups were compared.Result：Bone healing time，recurrence and rejection aspects in the study group were significantly higher than those in the control group， the differences between the two groups has statistical significance（P<0.05）.Conclusion：In the clinical treatment of limbs long bone benign bone tumors with pathological fracture，the application of locking plate combined with allograft bone surgical treatment，not only can enhance clinical curative effect，also can promote the patients into bone，bone defect repairing effect，reduce the rejection rate，play a positive therapeutic effect.

2015 Vol. 12　(27):　53-55 [Abstract]（ 696 ） HTML (1 KB)  PDF  (687 KB)  ( 212 )

Objective：To explore the nursing of bronchial relaxation test in patients with cough variant asthma（ CVA）.Method：60 CVA cases of baseline FEV1<70% expected value were chosen， and pulmonary function were determined after inhaling albuterol 200-400 μg， and they were given nursing from making an appointment to end of checking.Result：60 cases completed examination，positive in 52 patients，accounted for 86.67%.Conclusion：Bronchial diastolic test is one of the specific inspection method of cough variant asthma.For patients with intractable cough with bronchial relaxation tests help to confirm the diagnosis of cough variant asthma.Complete test and ensure the accuracy of the results，nursing has an important role.

2015 Vol. 12　(27):　59-60 [Abstract]（ 671 ） HTML (1 KB)  PDF  (659 KB)  ( 211 )

Objective：To discuss the resection perioperative nursing procedure of endoscopy approaching pituitary adenomas through transsphenoidal.Method：The experience of 230 patients’ resection perioperative nursing of endoscopy approaching pituitary adenomas through transsphenoidal under the condition of general anesthesia from Feb 13， 2009 to Dec 13， 2013 were summed up.Result：230 cases had no serious complications during perioperative nursing. Conclusion：Adequate preparation before surgery and post-operative care can reduce the occurrence of pituitary adenoma patients undergoing operative complications.

2015 Vol. 12　(27):　63-65 [Abstract]（ 624 ） HTML (1 KB)  PDF  (688 KB)  ( 355 )

Objective： To observe the curative effect of psychological nursing for the patients with mild traumatic brain injuries with depression and anxiety. Method：40 patients with mild traumatic brain injuries with obvious symptoms of depression and anxiety were treated with psychological nursing. Before and after treatment， the symptoms of patients，the scores of self-report symptom inventory checklist 90（ SCL-90） and the nursing effect were compared. Result： The depression and anxiety symptoms of patients with mild traumatic brain injuries were significantly relieved，the SCL-90 scores before and after treatment was compared， the difference was statistically significant（P<0.01）.Conclusion： The targeted psychological care for patients of mild traumatic brain injuries with depression and anxiety， can effectively relieve the clinical symptoms and SCL-90 scores，it has important clinical significance.

2015 Vol. 12　(27):　69-71 [Abstract]（ 697 ） HTML (1 KB)  PDF  (690 KB)  ( 209 )

Objective：To investigate applications and care efficacy in patients with advanced pancreatic head carcinoma. Method：Microwave therapy was employed in forty-seven patients with unresectable advanced pancreatic head carcinoma ，and careful nursing intervention was offered . The efficacy was recorded. Result：There were 18 casesachieving pain relief；9 cases achieving significant improvement of jaundice；7 cases achieving bloating relief； 12 cases achieving significant improvement of discomfortsymptoms. Conclusion：Microwave therapy and careful nursing intervention could relieve effectively pain and discomfort in patients with advanced pancreatic head carcinoma.

2015 Vol. 12　(27):　74-77 [Abstract]（ 597 ） HTML (1 KB)  PDF  (709 KB)  ( 378 )

Objective： To summarize the research advancements and development trend of nursing risk causes and measures in recent 10 years. Method： In the abstract search column of the website www.cnki.net ， two key words of“ digestive internal medicine” and“ nursing risks”were input to search for relative papers. Then after artificial identification， 60 papers concerning digestive nursing risks were finally obtained.Next， statistical analysis， comparative analysis， and contrast were conducted. Result：The results showed the acquisition and attention levels of nursing risks by the nurse staff， the distribution span of the researchers， the breadth and depth of their researches， and the research defects as well in some way determined and guided our research trends and directions. Conclusion： Under new historical background， all clinical units integrating with their practical working conditions， should learn to study， exchange and innovate their working conducts， so as to predict the nursing risks and take measures against them in advance.Also， hospitals should adopt various operating and management models to perfect their nursing backgrounds so as to provide well-equipped and well-served treatment places for the patients， which will be an effective way to maintain harmonious doctor-patient relationship， reduce medical disputes， control nursing risks，ensure nursing qualities and clinical safety， it is an effective way to reduce the risk of nursing in the digestive medicine department.

2015 Vol. 12　(27):　80-83 [Abstract]（ 719 ） HTML (1 KB)  PDF  (707 KB)  ( 515 )

Objective：To study the effect of two methods of diaper creams and sanguisorba oil to prevent crissum skin damage from enternal nutrition cid-associated diarrhea in ICU.Method：From June 2012 to June 2013，there were 80 ICU patients with enternal nutrition cid-associated diarrhea chosen in our study. They were randomly divided into two groups. One group was treated with diaper creams，and the other group was treated with sanguisorba oil.Each group enrolled 40 patients separately.The two groups of patiens were treated according to operational standard. Observed and compared the incidence，occurrence time and severity of crissum skin damage. Result：The incidence of crissum skin damage of patients treated with diaper creams was 40.0%（16/40）， and patients treated with sanguisorba oil was 12.5%（5/40）.The difference was significant（P<0.05）.The occurrence time of crissum skin damage of patients treated with diaper creams was（ 2.46±1.95）d and patients treated with sanguisorba oil was（ 2.13±1.21）d.The occurrence time of crissum skin damage in two groups was no significant difference.The degree of crissum skin damage of patients treated with diaper creams was（ 3.29±0.52）points and patients treated with sanguisorba oil was（ 1.39±0.15）points.The degree of crissum skin damage of patients treated with diaper creams was significantly higher than patients with sanguisorba oil （P<0.05）. Conclusion：The treatment of sanguisorba oil can reduce the incidence and severity of skin damage，which is effective method to prevent crissum skin damage caused by enternal nutrition cid-associated diarrhea.

2015 Vol. 12　(27):　87-89 [Abstract]（ 684 ） HTML (1 KB)  PDF  (689 KB)  ( 657 )

Objective：To observe and investigate the effect of traditional Chinese and Western medicine on the inflammatory indexes of chronic pelvic inflammatory disease. Method：64 patients with chronic pelvic inflammatory disease in our hospital from June 2013 to June 2014 were selected and randomly divided into the observation group and the control group，with each group 32 patients.The observation group was treated with traditional Chinese and Western medicine，while the control group was treated with Western medicine alone.The clinical efficacy and the levels of inflammatory indexes of the two groups were observed and compared. Result： The total clinical effective rate of the observation group was better than that of the control group，the difference was statistically significant（P<0.05）.Before treatment，the differences in the expression levels of inflammatory between the two groups were not statistically significant（P>0.05）. After treatment，the levels of TNF-α，TGF-β1，IL-8 and IL-1β in the observation group were lower than those of the control group，the differences were statistically significant（P<0.05）. Conclusion：The traditional Chinese and Western medicine in the treatment of chronic pelvic inflammatory disease has a high effective rate and the improvement of the clinical inflammatory indexes are better，so it is worthy of clinical application.

2015 Vol. 12　(27):　94-95 [Abstract]（ 680 ） HTML (1 KB)  PDF  (669 KB)  ( 268 )

Objective：To establish self management guidelines and specification of home nursing therapy for patients in COPD when using the noninvasive ventilator ，to improve ability patients’ self management and life quality. Method：Sixty cases of standard patients for study were collected， and then they were divided into two groups. The control group was given routine health education mode while the testing group was given related knowledge and operation skill training before hospital discharge.After discharge of hospital，the standardization of self management guidelines was applied as a manual mission.The patients of two groups were tested by questionnaire of breathing self management ability and questionnaire of SGRQ life quality to test the self management and life quality after using noninvasive ventilator. Result：The difference of self management of control group and test group before intervention had no statistical significance（P>0.05）.While after six mouths’ intervention，the different self management questionnaire scores were statistically significant（P<0.05）. Conclusion：The self management guidelines of noninvasive ventilator and specification of home nursing therapy strengths patients’ ability of self management and improve the quality life of patients.

2015 Vol. 12　(27):　102-105 [Abstract]（ 673 ） HTML (1 KB)  PDF  (711 KB)  ( 460 )

Objective：To study the prediction effect of ECG in patients of anterior wall myocardial infarction with ST segment elevation and multivessel coronary artery disease.Method：88 patients with acute myocardial infarction were treated in our hospital from September 2013 to December 2014，according to artery imaging data and ECG before admission，the patients were divided into observation group and control group， the observation group of 48 cases with multi vessel coronary artery disease， while the control group of 40 cases with a single vessel lesion. The ECG and coronary artery imaging data of two groups before admission were analyzed，the effect of prediction on electrocardiogram in patients with anterior wall myocardial infarction with ST segment elevation and multivessel coronary artery disease were observed. Result：In ST segment elevation of two groups，aVL lead a total of 22 cases，the observation group of 13 cases， control group of 9 cases； V6 lead a total of 38 cases， 27 cases in the observation group， 11 cases in the control group，compared the ECG of aVL lead and V6 lead， the differences were statistically significance（P<0.05）. In the observation group，compared the degree of ST segment elevation and multiple coronary artery lesions，patients were mainly left anterior descending branch，the difference was no statistically significant（P>0.05）.Compared three lesions of ST segment elevation in 0.05-0.1 mV and ST segment elevation>0.1 mV， the difference was statistically significant（P<0.05）.The sensitivity，accuracy， and negative predictive value of ST elevation level>0.1 mV were better than the elevation of 0.05-0.1 mV， specificity was similar，the ST elevation level>0.1 mV of lower negative predictive value and higher positive predictive value. Conclusion： Electrocardiogram（ ECG） on the front wall ST segment elevation myocardial infarction patients with multivessel coronary artery lesions has high positive predictive value， multivessel coronary artery disease is closely related to the degree of anterior wall ST segment elevation.

2015 Vol. 12　(27):　109-111 [Abstract]（ 636 ） HTML (1 KB)  PDF  (691 KB)  ( 309 )

Objective：To analyze the sickbed allocation of clinical department，so as to optimize the sickbed allocation in hospital.Method：The 95% confidence interval was used to analyze the data and calculate the reasonable interval of sickbeds.Result：The sickbed allocation of 15 clinical departments in 30 clinical departments were suitable，9 clinical departments were insufficient，6 clinical departments were in surplus.Conclusion：Bed dynamic management，bed resources sharing， establishing medical association are all important measures to strengthen bed management.

2015 Vol. 12　(27):　115-117 [Abstract]（ 748 ） HTML (1 KB)  PDF  (687 KB)  ( 312 )

Objective： To measure the necrosis volume of avascular necrosis in femoral head by CT and MR imaging and to explore the correlation between the necrosis volume of avascular necrosis in femoral head and its clinical stages. Method：80 patients with avascular necrosis of femoral head in our hospital from March 2011 to March 2014 were selected as the research objects.All the patients were given the examination of CT and MR.The necrosis volumes of avascular necrosis in femoral head measured by CT and MR were compared.The relationship between the necrosis volume of avascular necrosis in femoral head and the clinical stages was analyzed.Result：The difference between the necrosis volume measured by CT and the necrosis volume measured by MR was not statistically significant（P>0.05）.As the percentage of necrotic volume making up the volume of femoral head ascended，the clinical stage of ARCO increased. Conclusion： CT and MR imaging can help the surgeons calculate the necrosis volume of avascular necrosis in femoral head，the necrosis volume of femoral head can e used to predict the clinical stage of ARCO，it is worth of clinical spreading.

2015 Vol. 12　(27):　120-122 [Abstract]（ 626 ） HTML (1 KB)  PDF  (767 KB)  ( 264 )

Objective： To observe and investigate the clinical application value of surgical treatment under hysteroscopy in the treatment of intrauterine lesions. Method：106 patients who were treated in our hospital for uterine cavity lesions from June 2013 to June 2014 were selected as the research objects.They were given corresponding surgical treatment under hysteroscopy.The situation during the surgical and the situation of follow up were observed.Result：The laparoscopy found that there were 47 cases with subserosal uterine fibroids，10 cases with pelvic adhesions，18 cases with tubal blockage，17 cases with ovarian cysts and 14 cases with uterine perforation and mass.There were 46 cases with mild pain，49 cases with moderate pain and 11 cases with vagus nerve stimulation symptoms.The average operation time was 24.5 minutes and the average bleeding volume was 31.5 mL.The patients were followed up for 6 months，104 cases were followed up successfully and 2 cases lost contract.Most patients’ clinical symptoms were significantly improved. Conclusion：Surgical treatment under hysteroscopy in the treatment of intrauterine lesions has a high clinical effect and the recovery speed is fast，it is worthy of clinical application.

2015 Vol. 12　(27):　126-127 [Abstract]（ 666 ） HTML (1 KB)  PDF  (658 KB)  ( 200 )

Objective：To explore the clinical effect of posterolateral and medial combined approaches in prone position in the treatment of three ankle fracture. Method：56 patients with three ankle fracture in our hospital from June 2012 to December 2014 were selected as the research objects.All patients were treated with posterolateral and medial combined approaches in prone position.The clinical therapeutic effect and the related indexes were observed.Result：All patients received accurate follow-up after surgical treatment.The follow-up time was 5 to 25 months，the mean followup time was 11.3 months.The healing time of the fracture was 2 to 5 months，the average time was 4.1 months.The clinical therapeutic effect showed that the amount of patients with excellent，good and may was 29，22 and 5 respectively，the effective rate was 91.1%. Conclusion：Posterolateral and medial combined approaches in prone position in the treatment of three ankle fracture has the advantages of simple operation，reliable and good clinical effect.It is worth promotion and application in clinic.

2015 Vol. 12　(27):　132-133 [Abstract]（ 612 ） HTML (1 KB)  PDF  (658 KB)  ( 327 )

Objective： To evaluate application value of ¹⁸F-FDG PET-CT in diagnosing recurrent gynecologic carcinoma. Method： We chose 30 patients with gynecologic carcinoma after diagnosing and divided these patients into two groups. The first group contained 10 cases， they underwent the ¹⁸F-FDG PET-CT to examine the recurrent carcinoma after treatment. The second group contained 20 cases， and they were suspicious of recurrence in the clinic and they underwent the ¹⁸F-FDG PET-CT. Result： In the first group， there were 8 cases were negative results after undergoing the ¹⁸F-FDG PET-CT， including 1 case was positive result when undergoing the second ¹⁸F-FDG PET-CT examine， and proved to be digestive system cancer， 2 cases with positive result were diagnosed post-treatment changes. In the second group， 15 cases were positive results and 3 cases were proved to recurrent or move by operation， and the other 12 cases were given chemotherapy or radiotherapy， then 7 patients’ recurrent tumor volume reduced， and 2 cases died， 3 patients’ tumor had no change. The other 5 cases were negative results， but 2 cases changed to be positive results after the second examination and proved to be recurrent carcinoma. Conclusion： The ¹⁸F-FDG PET-CT examination is helpful to diagnose and treat the recurrent carcinoma earlier. It can reduce the pain of the patients and mortality， it is an effective method of monitoring of gynecologic carcinoma recurrence， and has important clinical significance to formulate and adjust the treatment plan in the
clinic.

2015 Vol. 12　(27):　136-139 [Abstract]（ 660 ） HTML (1 KB)  PDF  (722 KB)  ( 456 )

Objective：To discuss the feasibility of EnCor vacuum assisted biopsy system in the extraction operation of polyacrylamide-hydrogel-injected breast augmentation， and to assess the results of the operations. Method：43 breasts of 23 patients who had polyacrylamide-hydrogel-injected breast augmentation suffered from post operation complications，PAHG extraction under EnCor vacuum assisted biopsy system guided by B-Ultrasonic was conducted for all the patients.Result： The majority of PAHG in 43 breasts were removed under EnCor vacuum-assisted biopsy system.After 3-6 months follow-up，only two breasts of 2 cases had few PAHG focal low echo nodular residues by B-Ultrasonic.Conclusion：The majority of PAHG can be removed under EnCor vacuum-assisted biopsy system.The extraction operation is less injury，safe and reliable.It has application value in clinic.

2015 Vol. 12　(27):　144-146 [Abstract]（ 578 ） HTML (1 KB)  PDF  (847 KB)  ( 412 )

Hyponatremia is one of the most common water salt disbalance ， it is caused by a lot of the factors.If it is serious that can endanger life， and the fatality rate rate is very high. Therefore， it is important that will help the clinician correctly identify an deal with the patients suffering from hyponatremia，and then improve the survival rate of the patients and decrease death rate，and shorten the hospitalization days. In recentyears， attention has been gradually more paid in clinical practice to hyponatremia especially the emergency ， and hyponatremia diagnosis and treatment are also gradually improved， Here is to make a review on the progress of diagnosis and treatment of hyponatremia.

2015 Vol. 12　(27):　150-153 [Abstract]（ 555 ） HTML (1 KB)  PDF  (708 KB)  ( 506 )